C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dedicator of cytokinesis 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000128512 DOCK4 9606 - 7:111726110-112206411 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000417165 DOCK4-010 111769657-111789024 protein_coding
  ENST00000423057 DOCK4-007 111726110-111877128 protein_coding
  ENST00000428053 DOCK4-014 111760224-111784426 nonsense_mediated_decay
  ENST00000428084 DOCK4-005 111726478-112206411 protein_coding
  ENST00000437129 DOCK4-013 111765155-111784428 protein_coding
  ENST00000437633 DOCK4-001 111728220-112206395 protein_coding
  ENST00000445943 DOCK4-004 111728274-112004131 protein_coding
  ENST00000450156 DOCK4-012 111765196-111784479 protein_coding
  ENST00000464338 DOCK4-011 111778327-111788920 retained_intron
  ENST00000468571 DOCK4-003 111976538-112004132 processed_transcript
  ENST00000469898 DOCK4-017 111788501-111822424 retained_intron
  ENST00000476846 DOCK4-002 111862883-112206394 processed_transcript
  ENST00000486186 DOCK4-015 111726747-111740214 retained_intron
  ENST00000492436 DOCK4-009 111767081-111789260 processed_transcript
  ENST00000492532 DOCK4-008 111869460-111872347 processed_transcript
  ENST00000494651 DOCK4-201 111728273-112004132 protein_coding
  ENST00000494769 DOCK4-016 111728421-111732514 processed_transcript

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000423057ENST00000428084ENST00000437633ENST00000445943ENST00000468571ENST00000476846ENST00000492436
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000423057 N/A N/A N/A 2.634±0.00 N/A 0.369±0.00 N/A 0.293±0.00 N/A N/A N/A 0.853±0.00 N/A N/A
ENST00000428084 1.478±0.00 N/A N/A 2.501±0.01 1.659±0.00 N/A 0.341±0.00 0.880±0.00 0.513±0.00 3.504±0.00 N/A 1.441±0.00 0.557±0.00 N/A
ENST00000437633 1.311±0.00 1.058±0.00 2.066±0.00 4.491±1.76 2.597±0.00 1.001±0.00 0.973±0.17 2.018±0.00 1.375±0.00 9.773±0.00 0.061±0.00 1.366±0.62 0.606±0.00 0.461±0.00
ENST00000445943 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.981±0.00 N/A N/A N/A
ENST00000468571 N/A N/A N/A N/A N/A 4.011±0.00 N/A 5.127±0.00 N/A N/A N/A N/A N/A N/A
ENST00000476846 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.087±0.00 N/A N/A N/A
ENST00000492436 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.908±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005515 IPI:IEA protein binding
GO:0005622 IEA intracellular
GO:0005829 IDA cytosol
GO:0007165 IEA signal transduction
GO:0007264 IEA small GTPase mediated signal transduction
GO:0016020 IDA membrane
GO:0017124 IEA SH3 domain binding
GO:0030165 IPI PDZ domain binding
GO:0030675 IDA Rac GTPase activator activity
GO:0030971 IPI receptor tyrosine kinase binding
GO:0032420 ISS stereocilium
GO:0032421 ISS stereocilium bundle
GO:0032855 IDA positive regulation of Rac GTPase activity
GO:0043547 IEA positive regulation of GTPase activity
GO:0048365 IDA Rac GTPase binding
GO:0060326 IMP cell chemotaxis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000024874 dock4b dedicator of cytokinesis 4b protein_coding Danio_rerio
ENSDARG00000076213 DOCK4 (2 of 2) dedicator of cytokinesis 4 protein_coding Danio_rerio
ENSMUSG00000035954 Dock4 dedicator of cytokinesis 4 protein_coding Mus_musculus

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