C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dedicator of cytokinesis 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000035954 Dock4 10090 + 12:40446053-40846486 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000037488 Dock4-201 40446053-40846486 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000037488
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000037488 3.409±0.56 4.219±0.81 2.009±0.20 10.405±0.55 1.709±0.74 0.770±0.33 1.467±0.92 2.375±0.59 1.892±1.71 15.950±1.89 1.195±0.31 8.321±2.76 0.539±0.44 0.248±0.07

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005829 ISS cytosol
GO:0007264 IEA small GTPase mediated signal transduction
GO:0016020 ISS membrane
GO:0017124 IEA SH3 domain binding
GO:0030165 IEA PDZ domain binding
GO:0030675 IEA Rac GTPase activator activity
GO:0030971 IEA receptor tyrosine kinase binding
GO:0032420 IDA stereocilium
GO:0032421 IDA stereocilium bundle
GO:0032855 IEA positive regulation of Rac GTPase activity
GO:0048365 IEA Rac GTPase binding
GO:0060326 ISS cell chemotaxis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000024874 dock4b dedicator of cytokinesis 4b protein_coding Danio_rerio
ENSDARG00000076213 DOCK4 (2 of 2) dedicator of cytokinesis 4 protein_coding Danio_rerio
ENSG00000128512 DOCK4 dedicator of cytokinesis 4 protein_coding Homo_sapiens

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