C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000129355 CDKN2D 9606 - 19:10566462-10569059 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000335766 CDKN2D-002 10566601-10569059 protein_coding
  ENST00000393599 CDKN2D-001 10566462-10568978 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000335766ENST00000393599
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000335766 11.717±0.00 14.276±0.00 0.285±0.00 20.448±14.82 5.436±0.00 5.135±4.94 1.630±1.30 2.863±2.15 1.316±0.00 14.602±13.89 1.850±1.76 2.789±1.29 6.017±0.96 21.846±2.70
ENST00000393599 2.092±0.00 6.208±0.00 N/A 7.803±0.28 0.729±0.23 1.101±0.98 1.866±0.00 1.546±0.00 0.474±0.28 8.133±8.04 1.610±0.00 1.467±1.10 2.383±1.05 3.930±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000493 CIL_000493_0001 CGP 19:10553078-10569059
CIL_000494 CIL_000494_0001 CGP 19:10566462-10587315

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000079 IDA regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000082 IDA G1/S transition of mitotic cell cycle
GO:0000278 TAS mitotic cell cycle
GO:0000731 IMP DNA synthesis involved in DNA repair
GO:0004861 IDA cyclin-dependent protein serine/threonine kinase inhibitor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0007050 IDA cell cycle arrest
GO:0007605 IEA sensory perception of sound
GO:0008285 IDA negative regulation of cell proliferation
GO:0009411 IMP response to UV
GO:0019901 IPI protein kinase binding
GO:0030308 IDA negative regulation of cell growth
GO:0032526 IMP response to retinoic acid
GO:0033280 IMP response to vitamin D
GO:0042326 IDA negative regulation of phosphorylation
GO:0043154 IMP negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0048102 IMP autophagic cell death
GO:0071901 IDA negative regulation of protein serine/threonine kinase activity
GO:1902230 IMP negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000094176 cdkn2d cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) protein_coding Danio_rerio
ENSMUSG00000096472 Cdkn2d cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) protein_coding Mus_musculus

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