C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: spermidine/spermine N1-acetyltransferase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000130066 SAT1 9606 + X:23783158-23786226 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000379251 SAT1-004 23783173-23784213 protein_coding
  ENST00000379253 SAT1-003 23783173-23784411 protein_coding
  ENST00000379254 SAT1-005 23783173-23786113 protein_coding
  ENST00000379270 SAT1-001 23783173-23786226 protein_coding
  ENST00000462639 SAT1-007 23785260-23786210 processed_transcript
  ENST00000463236 SAT1-009 23783337-23786109 processed_transcript
  ENST00000474223 SAT1-006 23784753-23786000 processed_transcript
  ENST00000487713 SAT1-008 23783508-23784029 processed_transcript
  ENST00000489394 SAT1-002 23783197-23786210 processed_transcript
  ENST00000612412 SAT1-201 23783158-23786208 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000379251ENST00000379253ENST00000379254ENST00000379270ENST00000463236ENST00000474223ENST00000489394
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000379251 N/A N/A N/A N/A N/A N/A 4.142±0.00 N/A 7.308±0.00 31.485±0.00 N/A N/A N/A N/A
ENST00000379253 N/A N/A 25.774±0.00 16.135±0.00 N/A 27.257±0.00 4.946±0.00 40.802±0.00 N/A N/A N/A 193.091±146.35 N/A 26.450±0.00
ENST00000379254 N/A N/A N/A N/A N/A N/A N/A N/A N/A 332.810±0.00 N/A N/A N/A N/A
ENST00000379270 159.574±0.00 64.659±0.00 31.794±0.00 48.620±13.69 63.670±10.04 67.290±23.98 15.339±11.16 109.660±16.35 53.358±35.91 523.408±471.35 7.640±3.88 295.537±278.91 397.099±81.60 66.935±12.30
ENST00000463236 41.096±0.00 22.570±0.00 N/A 32.268±0.00 22.337±0.00 37.737±0.00 N/A 41.367±0.00 N/A N/A 3.951±0.00 N/A N/A 19.116±0.00
ENST00000474223 N/A 25.389±0.00 N/A N/A N/A N/A 14.260±0.00 28.524±0.00 25.927±0.00 N/A N/A 101.832±0.00 N/A N/A
ENST00000489394 N/A N/A N/A N/A N/A N/A 2.334±0.00 N/A N/A N/A N/A 29.693±18.53 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002L7 CIL_0002L7_0002 CGP X:23702253-23786226
CIL_0002WD CIL_0002WD_0002 CGP X:23783158-23907934

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEP angiogenesis
GO:0004145 IEA diamine N-acetyltransferase activity
GO:0005515 IPI protein binding
GO:0005622 IDA intracellular
GO:0005829 TAS cytosol
GO:0006595 TAS polyamine metabolic process
GO:0006596 TAS polyamine biosynthetic process
GO:0006598 IEA polyamine catabolic process
GO:0008080 IEA N-acetyltransferase activity
GO:0008152 IEA metabolic process
GO:0009447 IEA putrescine catabolic process
GO:0019809 IEA spermidine binding
GO:0032918 IEA spermidine acetylation
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042127 IEA regulation of cell proliferation
GO:0044281 TAS small molecule metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000032272 sat1b spermidine/spermine N1-acetyl transferase 1b protein_coding Danio_rerio
ENSDARG00000035652 sat1a.1 spermidine/spermine N1-acetyltransferase 1a, duplicate 1 protein_coding Danio_rerio
ENSMUSG00000025283 Sat1 spermidine/spermine N1-acetyl transferase 1 protein_coding Mus_musculus

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