C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: histidine rich calcium binding protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000130528 HRC 9606 - 19:49151198-49155424 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000252825 HRC-001 49151198-49155424 protein_coding
  ENST00000595167 HRC-004 49151955-49153307 retained_intron
  ENST00000595625 HRC-002 49151289-49155243 protein_coding
  ENST00000598858 HRC-003 49151199-49153435 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000252825ENST00000595625ENST00000598858
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000252825 1.843±0.00 2.191±0.00 0.210±0.00 0.432±0.30 6.590±0.00 2.992±0.00 110.093±83.22 1.022±0.90 0.505±0.00 0.952±0.79 120.442±107.58 1.243±0.92 1.467±0.99 3.601±3.55
ENST00000595625 N/A N/A N/A N/A 0.094±0.00 N/A 47.354±0.00 N/A 0.192±0.00 N/A N/A 0.038±0.00 N/A 0.246±0.00
ENST00000598858 N/A N/A N/A N/A N/A N/A N/A N/A 0.274±0.00 1.467±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003AT CIL_0003AT_0002 CGP 19:49151198-49211836

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002027 IMP regulation of heart rate
GO:0005509 IDA calcium ion binding
GO:0005515 IPI protein binding
GO:0006936 TAS muscle contraction
GO:0008016 IEA regulation of heart contraction
GO:0010460 IGI positive regulation of heart rate
GO:0010880 IGI regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0010881 TAS regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0030018 IDA Z disc
GO:0033017 IEA sarcoplasmic reticulum membrane
GO:0033018 TAS sarcoplasmic reticulum lumen
GO:0033135 IGI regulation of peptidyl-serine phosphorylation
GO:0044325 IPI ion channel binding
GO:0045823 IGI positive regulation of heart contraction
GO:0051117 IPI ATPase binding
GO:0051480 IGI cytosolic calcium ion homeostasis
GO:0055074 IEA calcium ion homeostasis
GO:0060314 IGI regulation of ryanodine-sensitive calcium-release channel activity
GO:1901844 IGI regulation of cell communication by electrical coupling involved in cardiac conduction
GO:1901899 IGI positive regulation of relaxation of cardiac muscle
GO:1903169 IGI regulation of calcium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000045947 HRC histidine rich calcium binding protein protein_coding Danio_rerio
ENSMUSG00000038239 Hrc histidine rich calcium binding protein protein_coding Mus_musculus

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