C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000130741 EIF2S3 9606 + X:24054716-24077971 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000253039 EIF2S3-001 24054716-24077971 protein_coding
  ENST00000423068 EIF2S3-002 24054971-24060479 protein_coding
  ENST00000457332 EIF2S3-005 24073262-24077408 processed_transcript
  ENST00000460032 EIF2S3-003 24071713-24073528 processed_transcript
  ENST00000487075 EIF2S3-004 24054946-24062626 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000253039
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000253039 21.681±0.00 16.635±0.00 8.677±0.00 8.478±0.50 26.320±1.64 35.351±16.85 9.701±3.72 12.874±3.54 20.065±7.65 23.468±0.35 15.136±8.79 52.102±15.12 9.457±1.51 12.112±7.93

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002YT CIL_0002YT_0002 CGP X:23983720-24077971
CIL_0001JE CIL_0001JE_0002 CGP X:24054716-24216255

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003743 IDA translation initiation factor activity
GO:0003924 IEA GTPase activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005829 TAS cytosol
GO:0006184 IEA GTP catabolic process
GO:0006412 TAS translation
GO:0006413 IDA translational initiation
GO:0008135 IDA translation factor activity, nucleic acid binding
GO:0010467 TAS gene expression
GO:0044267 TAS cellular protein metabolic process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008292 eif2s3 eukaryotic translation initiation factor 2, subunit 3 gamma protein_coding Danio_rerio
ENSMUSG00000035150 Eif2s3x eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked protein_coding Mus_musculus

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