C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: amine oxidase, copper containing 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000131471 AOC3 9606 + 17:42851184-42858130 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000308423 AOC3-001 42851184-42858124 protein_coding
  ENST00000587330 AOC3-003 42852753-42856301 nonsense_mediated_decay
  ENST00000588033 AOC3-005 42854127-42855522 protein_coding
  ENST00000591562 AOC3-002 42854078-42858130 protein_coding
  ENST00000592999 AOC3-004 42853277-42856343 protein_coding
  ENST00000613571 AOC3-201 42851184-42858128 protein_coding
  ENST00000617500 AOC3-202 42853243-42858128 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000308423ENST00000591562ENST00000592999ENST00000613571ENST00000617500
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000308423 49.012±0.00 31.953±0.00 1.538±0.00 0.850±0.00 89.039±83.95 11.832±10.82 1.782±1.09 4.776±0.00 8.777±0.00 39.644±34.46 2.788±0.00 10.842±7.72 17.854±10.50 25.863±0.00
ENST00000591562 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.798±0.00
ENST00000592999 N/A N/A N/A N/A N/A N/A N/A N/A N/A 8.281±0.00 N/A N/A N/A N/A
ENST00000613571 N/A N/A 0.542±0.00 N/A N/A 11.538±4.52 1.765±0.94 1.690±0.00 6.927±4.69 14.996±10.74 2.911±0.35 4.434±1.68 6.424±4.10 6.405±0.00
ENST00000617500 44.398±0.00 32.627±0.00 1.375±0.00 0.613±0.58 161.121±0.00 54.610±0.00 2.229±0.00 7.938±0.00 2.119±0.00 55.666±0.00 2.114±0.00 15.029±0.42 3.686±0.00 36.383±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004MM CIL_0004MM_0001 CGP 17:42844600-42858130
CIL_00044T CIL_00044T_0001 CGP 17:42851184-42913369

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005261 IDA cation channel activity
GO:0005507 IEA:IDA copper ion binding
GO:0005509 IDA calcium ion binding
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0005902 IDA microvillus
GO:0006812 IDA cation transport
GO:0006954 TAS inflammatory response
GO:0007155 IDA cell adhesion
GO:0008131 IEA:IDA primary amine oxidase activity
GO:0009308 IEA:IDA amine metabolic process
GO:0009986 IDA cell surface
GO:0016021 IDA integral component of membrane
GO:0042803 TAS protein homodimerization activity
GO:0046677 IDA response to antibiotic
GO:0046982 IPI protein heterodimerization activity
GO:0048038 IEA:IDA quinone binding
GO:0052593 IEA tryptamine:oxygen oxidoreductase (deaminating) activity
GO:0052594 IEA aminoacetone:oxygen oxidoreductase(deaminating) activity
GO:0052595 IEA aliphatic-amine oxidase activity
GO:0052596 IEA phenethylamine:oxygen oxidoreductase (deaminating) activity
GO:0055114 IEA oxidation-reduction process
GO:0098655 IDA cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014646 aoc2 amine oxidase, copper containing 2 protein_coding Danio_rerio
ENSMUSG00000019326 Aoc3 amine oxidase, copper containing 3 protein_coding Mus_musculus

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