C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: anoctamin 1, calcium activated chloride channel
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000131620 ANO1 9606 + 11:70078302-70189528 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000316296 ANO1-002 70085414-70163577 protein_coding
  ENST00000355303 ANO1-001 70078302-70189528 protein_coding
  ENST00000525494 ANO1-005 70169965-70188066 processed_transcript
  ENST00000529636 ANO1-009 70165362-70180045 retained_intron
  ENST00000529913 ANO1-010 70104129-70116579 retained_intron
  ENST00000530480 ANO1-007 70103097-70132033 protein_coding
  ENST00000530676 ANO1-003 70085422-70189252 protein_coding
  ENST00000531300 ANO1-008 70141594-70161642 protein_coding
  ENST00000531349 ANO1-004 70108185-70189252 protein_coding
  ENST00000531604 ANO1-006 70078573-70111761 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000316296ENST00000355303ENST00000525494ENST00000529636ENST00000530480ENST00000530676ENST00000531300ENST00000531604
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000316296 N/A N/A N/A 0.030±0.00 N/A 0.486±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000355303 3.368±0.00 2.231±0.00 N/A N/A 4.826±3.92 2.985±2.55 2.580±0.00 2.130±0.00 0.855±0.00 6.033±0.00 1.400±0.00 3.068±2.07 0.926±0.28 10.554±0.00
ENST00000525494 N/A N/A 0.613±0.00 0.094±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000529636 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 9.829±0.00 4.045±0.00 15.183±0.00
ENST00000530480 N/A N/A N/A 0.172±0.00 5.033±0.00 N/A 1.238±0.00 27.095±0.00 3.380±0.00 N/A 1.271±0.00 3.815±0.00 N/A N/A
ENST00000530676 N/A N/A N/A N/A N/A N/A N/A 0.882±0.00 N/A N/A 0.314±0.00 N/A N/A 3.126±0.00
ENST00000531300 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.441±0.00 N/A N/A N/A
ENST00000531604 N/A N/A N/A N/A N/A N/A 0.747±0.00 N/A 2.627±0.00 1.959±0.00 2.451±0.00 2.637±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000SL CIL_0000SL_0002 CGP 11:70078302-70207390

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005227 IDA calcium activated cation channel activity
GO:0005229 ISS intracellular calcium activated chloride channel activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005886 ISS plasma membrane
GO:0006812 IDA cation transport
GO:0006821 ISS chloride transport
GO:0009897 IEA external side of plasma membrane
GO:0016021 IEA integral component of membrane
GO:0016324 IEA apical plasma membrane
GO:0034220 TAS ion transmembrane transport
GO:0034707 IEA chloride channel complex
GO:0042391 IEA regulation of membrane potential
GO:0042803 IEA protein homodimerization activity
GO:0046982 IEA protein heterodimerization activity
GO:0055085 TAS transmembrane transport
GO:0070062 IDA extracellular vesicular exosome
GO:0098655 IDA cation transmembrane transport
GO:1902476 IEA chloride transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027075 ano1 anoctamin 1, calcium activated chloride channel protein_coding Danio_rerio
ENSDARG00000052372 ANO1 (2 of 4) anoctamin 1, calcium activated chloride channel protein_coding Danio_rerio
ENSDARG00000076141 CABZ01088346.1 Anoctamin protein_coding Danio_rerio
ENSMUSG00000031075 Ano1 anoctamin 1, calcium activated chloride channel protein_coding Mus_musculus

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