C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: anoctamin 1, calcium activated chloride channel
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031075 Ano1 10090 - 7:144588549-144751974 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000033393 Ano1-201 144588553-144738592 protein_coding
  ENSMUST00000118556 Ano1-001 144588549-144738566 protein_coding
  ENSMUST00000121758 Ano1-002 144588549-144738543 protein_coding
  ENSMUST00000131571 Ano1-007 144595442-144608295 retained_intron
  ENSMUST00000131731 Ano1-004 144655601-144678885 protein_coding
  ENSMUST00000141632 Ano1-005 144654095-144669377 retained_intron
  ENSMUST00000152531 Ano1-006 144621668-144669380 protein_coding
  ENSMUST00000155175 Ano1-003 144650503-144751974 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000033393ENSMUST00000121758ENSMUST00000131571ENSMUST00000131731ENSMUST00000152531ENSMUST00000155175
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000033393 4.183±2.70 6.689±1.81 N/A 2.693±0.40 5.280±1.66 8.511±0.96 0.935±0.48 1.722±0.61 0.483±0.25 6.363±1.38 0.246±0.00 18.392±3.89 0.906±0.00 4.128±2.10
ENSMUST00000121758 5.213±4.05 N/A 11.767±0.00 0.569±0.17 N/A N/A 1.276±0.17 0.876±0.40 0.400±0.20 4.411±0.00 0.912±0.43 8.938±2.36 0.949±0.69 1.477±0.70
ENSMUST00000131571 N/A N/A N/A N/A 40.204±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000131731 N/A N/A N/A N/A 17.551±0.77 40.851±7.04 N/A N/A N/A 25.715±0.00 N/A 28.372±3.20 N/A N/A
ENSMUST00000152531 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 17.374±0.00 N/A N/A
ENSMUST00000155175 N/A N/A N/A N/A N/A N/A N/A N/A 0.333±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005227 IEA calcium activated cation channel activity
GO:0005229 IDA intracellular calcium activated chloride channel activity
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005886 IDA plasma membrane
GO:0006812 IEA cation transport
GO:0006821 IDA chloride transport
GO:0009897 IDA external side of plasma membrane
GO:0016021 IEA integral component of membrane
GO:0016324 IDA apical plasma membrane
GO:0034707 IEA chloride channel complex
GO:0042391 IGI regulation of membrane potential
GO:0042803 IPI protein homodimerization activity
GO:0046982 IPI protein heterodimerization activity
GO:0060438 IMP trachea development
GO:0070062 IEA extracellular vesicular exosome
GO:0098655 IEA cation transmembrane transport
GO:1902476 IDA:IEA chloride transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027075 ano1 anoctamin 1, calcium activated chloride channel protein_coding Danio_rerio
ENSDARG00000052372 ANO1 (2 of 4) anoctamin 1, calcium activated chloride channel protein_coding Danio_rerio
ENSDARG00000076141 CABZ01088346.1 Anoctamin protein_coding Danio_rerio
ENSG00000131620 ANO1 anoctamin 1, calcium activated chloride channel protein_coding Homo_sapiens

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