C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lectin, galactoside-binding, soluble, 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000131981 LGALS3 9606 + 14:55124110-55145413 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000254301 LGALS3-001 55129044-55145403 protein_coding
  ENST00000553493 LGALS3-008 55124110-55138292 protein_coding
  ENST00000553755 LGALS3-007 55129256-55142755 processed_transcript
  ENST00000554715 LGALS3-003 55129260-55143721 protein_coding
  ENST00000556263 LGALS3-005 55138044-55140440 processed_transcript
  ENST00000556322 LGALS3-004 55137369-55142678 processed_transcript
  ENST00000556438 LGALS3-002 55137188-55145413 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000254301ENST00000553755ENST00000554715ENST00000556438
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000254301 103.132±0.00 46.546±0.00 3.101±1.61 100.264±57.56 84.267±35.70 55.314±47.92 28.716±28.52 5.034±0.62 127.052±111.05 14.912±14.39 224.949±143.11 141.844±96.22 16.855±12.10
ENST00000553755 N/A N/A N/A N/A N/A N/A N/A N/A 89.017±0.00 N/A 101.990±0.00 82.748±0.00 15.149±0.00
ENST00000554715 N/A N/A N/A N/A N/A N/A N/A N/A 3.442±0.00 4.638±0.00 N/A N/A N/A
ENST00000556438 N/A N/A N/A N/A 14.578±0.00 N/A N/A N/A 2.880±0.00 0.376±0.00 9.292±5.12 N/A 0.928±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004RO CIL_0004RO_0001 CGP 14:55051631-55145413
CIL_0000HY CIL_0000HY_0001 CGP 14:55124110-55191678

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001501 IEA skeletal system development
GO:0001772 IDA immunological synapse
GO:0002548 IDA monocyte chemotaxis
GO:0005515 IPI protein binding
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005615 IDA extracellular space
GO:0005634 IDA nucleus
GO:0005681 IEA spliceosomal complex
GO:0005737 IDA cytoplasm
GO:0005743 IDA mitochondrial inner membrane
GO:0005886 TAS plasma membrane
GO:0006397 IEA mRNA processing
GO:0008380 IEA RNA splicing
GO:0009897 IEA external side of plasma membrane
GO:0016020 IDA membrane
GO:0019863 IDA IgE binding
GO:0030198 IEA extracellular matrix organization
GO:0030246 IEA carbohydrate binding
GO:0030593 IDA neutrophil chemotaxis
GO:0030855 IEP epithelial cell differentiation
GO:0031012 IDA extracellular matrix
GO:0042056 IDA chemoattractant activity
GO:0042129 IMP regulation of T cell proliferation
GO:0043236 IDA laminin binding
GO:0044822 IDA poly(A) RNA binding
GO:0045087 TAS innate immune response
GO:0045806 IDA negative regulation of endocytosis
GO:0048245 IDA eosinophil chemotaxis
GO:0048246 IDA macrophage chemotaxis
GO:0050860 ISS negative regulation of T cell receptor signaling pathway
GO:0050918 IDA positive chemotaxis
GO:0070062 IDA extracellular vesicular exosome
GO:0070232 IDA regulation of T cell apoptotic process
GO:0071674 IDA mononuclear cell migration
GO:0071677 IDA positive regulation of mononuclear cell migration
GO:0090280 IDA positive regulation of calcium ion import
GO:1902041 IMP regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:2000521 ISS negative regulation of immunological synapse formation
GO:2001189 ISS negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
GO:2001237 IDA negative regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077850 LGALS3 lectin, galactoside-binding, soluble, 3 protein_coding Danio_rerio
ENSMUSG00000050335 Lgals3 lectin, galactose binding, soluble 3 protein_coding Mus_musculus

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