C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lectin, galactose binding, soluble 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000050335 Lgals3 10090 + 14:47367751-47386160 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000142734 Lgals3-001 47373813-47386160 protein_coding
  ENSMUST00000144794 Lgals3-004 47373916-47380317 protein_coding
  ENSMUST00000146468 Lgals3-003 47373974-47385794 protein_coding
  ENSMUST00000150290 Lgals3-002 47373899-47385799 protein_coding
  ENSMUST00000151405 Lgals3-005 47367751-47380418 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000142734ENSMUST00000146468ENSMUST00000150290ENSMUST00000151405
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000142734 17.901±8.52 N/A 16.610±1.83 0.211±0.16 15.790±6.59 192.315±45.89 0.666±0.24 4.494±1.06 2.098±1.46 19.292±3.15 0.213±0.00 13.562±4.22 27.566±0.00 N/A
ENSMUST00000146468 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.414±0.00 N/A N/A N/A
ENSMUST00000150290 99.733±38.75 32.015±2.96 148.680±6.72 0.629±0.38 93.448±44.63 1407.803±88.03 6.371±2.00 34.763±3.27 12.004±9.23 117.105±15.11 3.619±1.33 67.034±13.91 409.835±279.05 1.619±1.00
ENSMUST00000151405 N/A N/A N/A 0.192±0.08 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.098±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004RO CIL_0004RO_0002 CGP 14:47298314-47386160
CIL_0000HY CIL_0000HY_0002 CGP 14:47367751-47418407

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001501 IGI skeletal system development
GO:0001772 IEA immunological synapse
GO:0002548 IEA monocyte chemotaxis
GO:0005515 IPI protein binding
GO:0005578 IDA proteinaceous extracellular matrix
GO:0005615 IEA extracellular space
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005743 IEA mitochondrial inner membrane
GO:0009897 IDA external side of plasma membrane
GO:0016020 IEA membrane
GO:0019863 IEA IgE binding
GO:0030198 IGI extracellular matrix organization
GO:0030246 IEA carbohydrate binding
GO:0030593 IEA neutrophil chemotaxis
GO:0030855 IEA epithelial cell differentiation
GO:0031012 IEA extracellular matrix
GO:0042056 IEA chemoattractant activity
GO:0042129 IEA regulation of T cell proliferation
GO:0043236 IEA laminin binding
GO:0044822 IEA poly(A) RNA binding
GO:0045806 IEA negative regulation of endocytosis
GO:0048245 IEA eosinophil chemotaxis
GO:0048246 IEA macrophage chemotaxis
GO:0050918 IEA positive chemotaxis
GO:0070062 IEA extracellular vesicular exosome
GO:0070232 IEA regulation of T cell apoptotic process
GO:0071674 IEA mononuclear cell migration
GO:0071677 IEA positive regulation of mononuclear cell migration
GO:0090280 IEA positive regulation of calcium ion import
GO:1902041 IEA regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:2001237 IEA negative regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077850 LGALS3 lectin, galactoside-binding, soluble, 3 protein_coding Danio_rerio
ENSG00000131981 LGALS3 lectin, galactoside-binding, soluble, 3 protein_coding Homo_sapiens

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