C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: replication protein A1, 70kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000132383 RPA1 9606 + 17:1829702-1900082 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000254719 RPA1-001 1829984-1899554 protein_coding
  ENST00000570451 RPA1-003 1829971-1875705 protein_coding
  ENST00000571058 RPA1-002 1829702-1872483 protein_coding
  ENST00000571725 RPA1-007 1843920-1854274 processed_transcript
  ENST00000573924 RPA1-004 1872127-1879305 processed_transcript
  ENST00000573994 RPA1-005 1891650-1897536 retained_intron
  ENST00000574049 RPA1-006 1879035-1900082 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000254719ENST00000571058ENST00000573994ENST00000574049
Transcript ID Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000254719 1.877±0.00 1.426±0.00 3.240±0.00 2.133±0.92 0.909±0.00 3.646±0.00 1.227±0.00 N/A 38.927±0.00 12.287±6.97 10.467±12.21 11.547±8.91
ENST00000571058 N/A N/A N/A N/A N/A N/A N/A N/A N/A 26.636±0.00 46.121±0.00 35.252±0.00
ENST00000573994 3.268±0.00 3.519±0.00 N/A N/A N/A N/A N/A 4.456±0.00 4.817±0.00 6.471±0.00 N/A N/A
ENST00000574049 N/A N/A N/A N/A N/A N/A N/A N/A 1.468±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000278 TAS mitotic cell cycle
GO:0000718 TAS nucleotide-excision repair, DNA damage removal
GO:0000722 TAS telomere maintenance via recombination
GO:0000723 IMP telomere maintenance
GO:0000724 IMP double-strand break repair via homologous recombination
GO:0000730 TAS DNA recombinase assembly
GO:0000793 IEA condensed chromosome
GO:0000794 IEA condensed nuclear chromosome
GO:0000800 IEA lateral element
GO:0001673 IEA male germ cell nucleus
GO:0001701 IEA in utero embryonic development
GO:0003676 IEA nucleic acid binding
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003684 IDA damaged DNA binding
GO:0003697 IDA single-stranded DNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005662 IDA DNA replication factor A complex
GO:0005737 IDA cytoplasm
GO:0006260 IEA:IMP DNA replication
GO:0006261 TAS DNA-dependent DNA replication
GO:0006271 TAS DNA strand elongation involved in DNA replication
GO:0006281 TAS:IEA DNA repair
GO:0006283 TAS transcription-coupled nucleotide-excision repair
GO:0006284 IDA base-excision repair
GO:0006289 IMP nucleotide-excision repair
GO:0006297 TAS nucleotide-excision repair, DNA gap filling
GO:0006298 IMP mismatch repair
GO:0006302 TAS double-strand break repair
GO:0006310 TAS:IEA DNA recombination
GO:0007126 IEA meiotic nuclear division
GO:0008284 IEA positive regulation of cell proliferation
GO:0015629 IDA actin cytoskeleton
GO:0016605 IDA PML body
GO:0030097 IEA hemopoiesis
GO:0032201 TAS telomere maintenance via semi-conservative replication
GO:0046872 IEA metal ion binding
GO:0048873 IEA homeostasis of number of cells within a tissue
GO:0051276 IEA chromosome organization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003938 rpa1 replication protein A1 protein_coding Danio_rerio
ENSMUSG00000000751 Rpa1 replication protein A1 protein_coding Mus_musculus

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