C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: eukaryotic translation initiation factor 5A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000132507 EIF5A 9606 + 17:7306999-7312463 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000336452 EIF5A-002 7306999-7312463 protein_coding
  ENST00000336458 EIF5A-001 7307373-7312455 protein_coding
  ENST00000355068 EIF5A-003 7307326-7310453 retained_intron
  ENST00000416016 EIF5A-006 7308371-7312455 protein_coding
  ENST00000419711 EIF5A-004 7307974-7312455 protein_coding
  ENST00000571955 EIF5A-005 7307974-7312455 protein_coding
  ENST00000572815 EIF5A-011 7307582-7311868 protein_coding
  ENST00000573542 EIF5A-009 7307602-7312244 protein_coding
  ENST00000573714 EIF5A-010 7307993-7311615 protein_coding
  ENST00000575001 EIF5A-008 7307631-7310101 retained_intron
  ENST00000576930 EIF5A-007 7307540-7312455 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000336452ENST00000336458ENST00000419711ENST00000572815ENST00000573542ENST00000573714
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000336452 N/A N/A 6.380±0.00 N/A N/A N/A N/A N/A N/A 4.756±0.00 N/A N/A N/A 40.531±0.00
ENST00000336458 43.380±0.00 49.407±0.00 N/A 28.449±14.86 28.728±21.04 53.365±0.00 19.333±12.38 26.446±18.68 28.329±20.91 30.069±25.45 35.019±22.05 40.443±23.44 125.599±9.33 48.523±0.00
ENST00000419711 42.430±0.00 51.477±0.00 N/A 43.175±0.00 37.733±0.00 41.307±0.00 38.792±0.00 86.791±0.00 104.725±0.00 100.576±0.00 131.498±0.00 102.618±6.75 108.081±27.51 111.590±54.48
ENST00000572815 N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.943±0.00 N/A N/A N/A N/A
ENST00000573542 45.823±0.00 69.660±0.00 N/A 23.425±0.00 20.419±14.41 19.254±0.00 4.810±0.00 10.653±0.00 12.011±0.00 5.090±0.00 17.059±0.00 36.988±19.85 66.341±0.00 N/A
ENST00000573714 N/A N/A 18.502±0.00 N/A 13.315±0.00 34.171±0.00 N/A 12.225±0.00 N/A N/A N/A 52.188±37.33 80.436±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003723 IDA:IEA RNA binding
GO:0003746 IEA:ISS translation elongation factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005642 IDA annulate lamellae
GO:0005643 IDA nuclear pore
GO:0005737 IDA cytoplasm
GO:0005783 IEA endoplasmic reticulum
GO:0005829 TAS cytosol
GO:0006406 IMP mRNA export from nucleus
GO:0006452 IEA translational frameshifting
GO:0006611 IMP protein export from nucleus
GO:0006913 IMP nucleocytoplasmic transport
GO:0006915 IDA apoptotic process
GO:0008284 IGI positive regulation of cell proliferation
GO:0008612 IEA:TAS peptidyl-lysine modification to peptidyl-hypusine
GO:0016020 IDA membrane
GO:0017070 IDA U6 snRNA binding
GO:0043022 IEA ribosome binding
GO:0043687 TAS post-translational protein modification
GO:0044267 TAS cellular protein metabolic process
GO:0044822 IDA poly(A) RNA binding
GO:0045901 IEA:ISS positive regulation of translational elongation
GO:0045905 IEA positive regulation of translational termination
GO:0047485 IPI protein N-terminus binding
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000078812 Eif5a eukaryotic translation initiation factor 5A protein_coding Mus_musculus

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