C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: EPH receptor B2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000133216 EPHB2 9606 + 1:22710839-22915325 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000374627 EPHB2-004 22775178-22913752 protein_coding
  ENST00000374630 EPHB2-003 22710965-22913743 protein_coding
  ENST00000374632 EPHB2-002 22710970-22914270 protein_coding
  ENST00000400191 EPHB2-001 22710965-22915325 protein_coding
  ENST00000465676 EPHB2-005 22800240-22896478 processed_transcript
  ENST00000490436 EPHB2-006 22865159-22882840 processed_transcript
  ENST00000544305 EPHB2-201 22710839-22891265 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000374627ENST00000374630ENST00000374632ENST00000400191ENST00000465676ENST00000544305
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000374627 N/A N/A N/A N/A N/A N/A N/A N/A 0.045±0.00 N/A N/A N/A N/A N/A
ENST00000374630 N/A N/A N/A N/A 2.354±0.00 N/A N/A 0.042±0.00 0.300±0.23 0.328±0.00 N/A 3.834±0.00 2.914±0.77 0.641±0.00
ENST00000374632 0.750±0.00 N/A N/A 1.402±0.00 0.896±0.29 2.018±0.71 0.101±0.06 N/A 0.587±0.00 N/A 0.025±0.00 19.738±0.00 2.048±0.10 0.779±0.00
ENST00000400191 0.614±0.00 4.815±0.00 0.340±0.00 1.847±0.00 2.535±0.00 3.935±1.15 N/A 1.528±0.00 N/A 0.766±0.00 N/A 9.480±5.70 5.526±1.77 2.133±0.00
ENST00000465676 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.863±0.00 1.632±0.00 N/A N/A N/A
ENST00000544305 N/A N/A N/A N/A N/A 2.263±0.00 0.028±0.00 N/A N/A 0.225±0.00 N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000902 IEA cell morphogenesis
GO:0001525 ISS angiogenesis
GO:0001655 ISS urogenital system development
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004872 IEA receptor activity
GO:0005003 IEA ephrin receptor activity
GO:0005005 ISS transmembrane-ephrin receptor activity
GO:0005102 IEA receptor binding
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005887 IEA integral component of plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007399 TAS nervous system development
GO:0007411 ISS axon guidance
GO:0007413 ISS axonal fasciculation
GO:0007612 IEA learning
GO:0008046 IEA axon guidance receptor activity
GO:0009887 IEA organ morphogenesis
GO:0016021 IEA integral component of membrane
GO:0016310 ISS phosphorylation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0021631 IEA optic nerve morphogenesis
GO:0021952 IEA central nervous system projection neuron axonogenesis
GO:0022038 ISS corpus callosum development
GO:0030424 ISS axon
GO:0030425 ISS dendrite
GO:0031290 IEA retinal ganglion cell axon guidance
GO:0042472 ISS inner ear morphogenesis
GO:0043025 IEA neuronal cell body
GO:0048013 IEA ephrin receptor signaling pathway
GO:0048168 IEA regulation of neuronal synaptic plasticity
GO:0048170 IEA positive regulation of long-term neuronal synaptic plasticity
GO:0048593 IEA camera-type eye morphogenesis
GO:0050770 IEA regulation of axonogenesis
GO:0050771 IEA negative regulation of axonogenesis
GO:0050878 ISS regulation of body fluid levels
GO:0051965 ISS positive regulation of synapse assembly
GO:0060021 ISS palate development
GO:0060996 ISS dendritic spine development
GO:0060997 ISS dendritic spine morphogenesis
GO:0071679 ISS commissural neuron axon guidance

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021539 ephb2b eph receptor B2b protein_coding Danio_rerio
ENSDARG00000037373 ephb2a eph receptor B2a protein_coding Danio_rerio
ENSMUSG00000028664 Ephb2 Eph receptor B2 protein_coding Mus_musculus

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