C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Eph receptor B2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028664 Ephb2 10090 - 4:136647539-136835988 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000059287 Ephb2-002 136653608-136835956 protein_coding
  ENSMUST00000105845 Ephb2-001 136647539-136835988 protein_coding
  ENSMUST00000105846 Ephb2-003 136654646-136835843 protein_coding
  ENSMUST00000144573 Ephb2-005 136769392-136835974 retained_intron
  ENSMUST00000151502 Ephb2-006 136659687-136661652 retained_intron
  ENSMUST00000156558 Ephb2-004 136661463-136694040 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000059287ENSMUST00000105845ENSMUST00000105846ENSMUST00000151502ENSMUST00000156558
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000059287 8.442±3.15 7.701±1.14 1.888±0.31 7.337±4.47 1.892±0.55 12.053±0.70 0.290±0.04 2.940±0.24 0.156±0.12 0.844±0.08 0.079±0.05 4.036±1.12 0.273±0.12 0.173±0.06
ENSMUST00000105845 2.109±0.00 0.976±0.05 N/A 8.063±6.16 0.269±0.02 3.566±0.30 0.041±0.01 0.370±0.07 0.029±0.03 0.115±0.00 0.004±0.00 1.142±0.41 0.049±0.03 0.038±0.02
ENSMUST00000105846 8.190±2.05 7.767±0.60 1.433±0.27 10.678±6.57 2.473±1.11 15.374±3.33 0.129±0.02 1.709±0.69 0.153±0.12 0.850±0.13 0.044±0.00 6.201±2.06 0.329±0.07 0.131±0.04
ENSMUST00000151502 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.054±0.00 N/A 0.809±0.00 N/A
ENSMUST00000156558 N/A 16.735±1.74 N/A N/A 4.305±0.00 17.085±0.00 N/A N/A 0.080±0.02 N/A N/A 9.545±1.75 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000209 CIL_000209_0002 CGP 4:136622621-136835988

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000902 IGI cell morphogenesis
GO:0004872 IDA receptor activity
GO:0005003 IDA ephrin receptor activity
GO:0005005 TAS transmembrane-ephrin receptor activity
GO:0005102 IPI receptor binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005887 TAS integral component of plasma membrane
GO:0006468 IDA protein phosphorylation
GO:0007169 IDA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007411 IDA axon guidance
GO:0007612 IMP learning
GO:0008046 IDA axon guidance receptor activity
GO:0009887 IMP organ morphogenesis
GO:0018108 IDA peptidyl-tyrosine phosphorylation
GO:0021631 IMP optic nerve morphogenesis
GO:0021952 IMP central nervous system projection neuron axonogenesis
GO:0031290 IDA retinal ganglion cell axon guidance
GO:0043025 IDA neuronal cell body
GO:0048013 IDA ephrin receptor signaling pathway
GO:0048168 IMP regulation of neuronal synaptic plasticity
GO:0048170 IMP positive regulation of long-term neuronal synaptic plasticity
GO:0048593 IMP camera-type eye morphogenesis
GO:0050770 IDA regulation of axonogenesis
GO:0050771 IDA negative regulation of axonogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021539 ephb2b eph receptor B2b protein_coding Danio_rerio
ENSDARG00000037373 ephb2a eph receptor B2a protein_coding Danio_rerio
ENSG00000133216 EPHB2 EPH receptor B2 protein_coding Homo_sapiens

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