C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: elongator acetyltransferase complex subunit 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000134014 ELP3 9606 + 8:28089673-28191156 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000256398 ELP3-001 28092838-28191156 protein_coding
  ENST00000380353 ELP3-201 28093067-28191150 protein_coding
  ENST00000517975 ELP3-018 28158598-28190089 protein_coding
  ENST00000518112 ELP3-004 28093139-28190203 nonsense_mediated_decay
  ENST00000519261 ELP3-005 28093140-28190094 nonsense_mediated_decay
  ENST00000520011 ELP3-015 28129319-28132404 retained_intron
  ENST00000520110 ELP3-016 28118898-28158625 processed_transcript
  ENST00000520270 ELP3-009 28089673-28107964 protein_coding
  ENST00000520288 ELP3-007 28093222-28110422 protein_coding
  ENST00000521015 ELP3-010 28090231-28191156 protein_coding
  ENST00000521099 ELP3-008 28093447-28107944 protein_coding
  ENST00000521570 ELP3-011 28090346-28113173 protein_coding
  ENST00000521938 ELP3-012 28093148-28110913 retained_intron
  ENST00000522063 ELP3-019 28099838-28112701 processed_transcript
  ENST00000523357 ELP3-017 28158580-28190087 protein_coding
  ENST00000523687 ELP3-002 28093102-28190094 nonsense_mediated_decay
  ENST00000523760 ELP3-014 28093112-28113822 processed_transcript
  ENST00000524103 ELP3-003 28093112-28189992 protein_coding
  ENST00000537665 ELP3-202 28093067-28191150 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000256398ENST00000380353ENST00000517975ENST00000518112ENST00000519261ENST00000521015ENST00000521570ENST00000523760ENST00000524103ENST00000537665
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000256398 N/A N/A 0.634±0.00 2.408±0.00 1.550±0.00 N/A N/A 2.564±0.00 N/A N/A N/A 4.032±0.00 N/A 1.825±0.00
ENST00000380353 N/A N/A N/A 2.355±0.00 N/A 1.183±0.00 N/A N/A 2.562±0.00 1.578±0.00 0.786±0.00 1.065±0.00 1.734±0.28 2.139±0.00
ENST00000517975 3.953±0.00 8.309±0.00 3.100±0.00 N/A N/A N/A N/A N/A N/A 2.387±0.00 N/A N/A N/A N/A
ENST00000518112 N/A N/A N/A N/A 0.931±0.00 N/A 1.386±0.43 N/A N/A N/A 0.635±0.00 3.057±0.04 3.672±1.55 N/A
ENST00000519261 N/A N/A N/A N/A 1.163±0.00 2.165±0.00 N/A N/A 1.886±0.00 1.600±0.29 N/A 2.857±0.00 2.871±0.00 6.553±0.00
ENST00000521015 3.112±0.00 N/A N/A 3.231±0.00 5.215±0.00 1.796±0.00 N/A 3.813±0.00 N/A N/A 5.954±0.00 5.099±1.80 6.359±0.00 5.125±0.00
ENST00000521570 N/A N/A N/A N/A N/A 4.060±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000523760 N/A N/A 2.644±0.00 N/A 2.315±0.00 2.880±0.00 2.549±0.00 N/A 6.960±0.00 4.893±0.00 1.427±0.00 3.245±0.00 N/A N/A
ENST00000524103 3.381±0.00 2.863±0.00 0.933±0.00 7.568±2.10 3.813±2.31 3.070±0.00 1.926±0.00 2.832±1.19 N/A 0.946±0.00 1.634±0.00 2.624±1.01 4.427±0.00 5.409±2.54
ENST00000537665 N/A 4.769±0.00 N/A N/A 2.067±0.00 N/A N/A N/A N/A 0.656±0.00 6.791±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009DK CIL_0009DK_0001 VISTA 8:27594923-28195834

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IDA DNA binding
GO:0003824 IEA catalytic activity
GO:0004402 IEA histone acetyltransferase activity
GO:0005515 IPI protein binding
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0006325 TAS chromatin organization
GO:0006357 TAS regulation of transcription from RNA polymerase II promoter
GO:0006368 IDA transcription elongation from RNA polymerase II promoter
GO:0008023 IDA transcription elongation factor complex
GO:0008080 IEA N-acetyltransferase activity
GO:0008152 IEA metabolic process
GO:0008607 IDA phosphorylase kinase regulator activity
GO:0016573 IEA histone acetylation
GO:0016591 IDA DNA-directed RNA polymerase II, holoenzyme
GO:0030335 ISS positive regulation of cell migration
GO:0033588 IDA Elongator holoenzyme complex
GO:0045859 IDA regulation of protein kinase activity
GO:0046872 IEA metal ion binding
GO:0051536 IEA iron-sulfur cluster binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042005 elp3 elongation protein 3 homolog (S. cerevisiae) protein_coding Danio_rerio
ENSMUSG00000022031 Elp3 elongator acetyltransferase complex subunit 3 protein_coding Mus_musculus

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