C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cyclin-dependent kinase 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000134058 CDK7 9606 + 5:69234841-69277430 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000256443 CDK7-001 69234873-69277430 protein_coding
  ENST00000502604 CDK7-003 69235117-69277338 protein_coding
  ENST00000504147 CDK7-009 69234958-69262294 nonsense_mediated_decay
  ENST00000506563 CDK7-005 69234841-69272904 protein_coding
  ENST00000506789 CDK7-010 69234892-69262207 nonsense_mediated_decay
  ENST00000508726 CDK7-013 69234969-69276569 nonsense_mediated_decay
  ENST00000510106 CDK7-011 69234898-69272951 nonsense_mediated_decay
  ENST00000512687 CDK7-002 69234861-69256021 retained_intron
  ENST00000512985 CDK7-008 69234883-69235495 retained_intron
  ENST00000513629 CDK7-012 69235143-69272996 processed_transcript
  ENST00000514676 CDK7-004 69234912-69277305 protein_coding
  ENST00000515180 CDK7-007 69234887-69259874 nonsense_mediated_decay
  ENST00000515391 CDK7-006 69234879-69269293 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000256443ENST00000502604ENST00000504147ENST00000506789ENST00000508726ENST00000510106ENST00000512687ENST00000514676ENST00000515180ENST00000515391
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000256443 N/A N/A N/A 2.495±0.00 1.759±0.00 1.200±0.00 0.242±0.00 1.903±0.00 0.788±0.26 N/A N/A 3.531±1.50 9.353±3.44 N/A
ENST00000502604 N/A N/A 1.108±0.00 N/A N/A 0.490±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000504147 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.769±0.00 N/A N/A N/A
ENST00000506789 N/A N/A N/A N/A N/A N/A 2.956±0.00 N/A N/A 2.238±0.00 N/A N/A N/A N/A
ENST00000508726 4.899±0.00 N/A N/A 5.080±0.00 7.315±0.00 3.840±0.00 N/A 4.012±2.74 N/A N/A N/A N/A 20.571±0.00 22.337±9.08
ENST00000510106 N/A N/A N/A N/A N/A N/A N/A N/A 0.883±0.00 N/A N/A N/A N/A N/A
ENST00000512687 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.614±0.00 N/A N/A
ENST00000514676 1.184±0.00 1.602±0.00 N/A 3.112±0.00 2.402±0.00 2.280±0.00 2.249±0.00 3.217±2.93 1.930±0.00 1.353±0.03 2.214±1.39 11.188±8.30 21.316±15.76 37.380±0.00
ENST00000515180 N/A N/A N/A 3.550±0.00 3.448±0.00 N/A 3.070±0.00 N/A N/A N/A 0.766±0.00 N/A N/A N/A
ENST00000515391 N/A N/A N/A N/A 2.105±0.00 N/A N/A N/A N/A N/A N/A 1.035±0.00 13.122±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000079 TAS regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000086 TAS G2/M transition of mitotic cell cycle
GO:0000278 TAS mitotic cell cycle
GO:0000718 TAS nucleotide-excision repair, DNA damage removal
GO:0003713 NAS transcription coactivator activity
GO:0004672 TAS:IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004693 IEA cyclin-dependent protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005675 IDA holo TFIIH complex
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0006200 IDA ATP catabolic process
GO:0006281 TAS DNA repair
GO:0006283 TAS transcription-coupled nucleotide-excision repair
GO:0006289 TAS nucleotide-excision repair
GO:0006360 TAS transcription from RNA polymerase I promoter
GO:0006361 TAS transcription initiation from RNA polymerase I promoter
GO:0006362 TAS transcription elongation from RNA polymerase I promoter
GO:0006363 TAS termination of RNA polymerase I transcription
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006368 TAS transcription elongation from RNA polymerase II promoter
GO:0006370 TAS 7-methylguanosine mRNA capping
GO:0006468 IEA protein phosphorylation
GO:0007050 TAS cell cycle arrest
GO:0008022 IPI protein C-terminus binding
GO:0008094 IDA DNA-dependent ATPase activity
GO:0008283 TAS cell proliferation
GO:0008353 IDA RNA polymerase II carboxy-terminal domain kinase activity
GO:0010467 TAS gene expression
GO:0016032 TAS viral process
GO:0016301 IEA kinase activity
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0030521 NAS androgen receptor signaling pathway
GO:0045893 NAS positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0050434 TAS positive regulation of viral transcription
GO:0050681 NAS androgen receptor binding
GO:0051301 IEA cell division

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000051916 cdk7 cyclin-dependent kinase 7 protein_coding Danio_rerio
ENSMUSG00000069089 Cdk7 cyclin-dependent kinase 7 protein_coding Mus_musculus

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