C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000134248 LAMTOR5 9606 - 1:110401249-110407942 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000256644 LAMTOR5-001 110401253-110407942 protein_coding
  ENST00000464240 LAMTOR5-002 110401249-110407694 retained_intron
  ENST00000474861 LAMTOR5-003 110401249-110407671 protein_coding
  ENST00000483260 LAMTOR5-004 110401249-110407668 protein_coding
  ENST00000531779 LAMTOR5-006 110403609-110407664 retained_intron
  ENST00000602318 LAMTOR5-007 110401253-110407708 protein_coding
  ENST00000602858 LAMTOR5-008 110401257-110406425 protein_coding
  ENST00000614544 LAMTOR5-201 110401257-110407924 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000464240ENST00000602318ENST00000602858ENST00000614544
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000464240 N/A N/A N/A N/A 0.803±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000602318 55.422±0.00 82.137±0.00 N/A 46.941±24.49 40.867±36.22 35.760±30.79 45.856±40.43 87.711±78.21 24.026±20.79 39.143±33.88 36.444±7.09 70.113±65.64 67.057±22.38 87.115±56.66
ENST00000602858 N/A N/A N/A N/A N/A N/A N/A N/A 4.168±0.00 N/A N/A N/A N/A N/A
ENST00000614544 N/A N/A 13.898±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005085 IDA guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005764 IDA lysosome
GO:0005829 IDA cytosol
GO:0008361 IMP regulation of cell size
GO:0009615 TAS response to virus
GO:0019079 IEA viral genome replication
GO:0032008 IMP positive regulation of TOR signaling
GO:0032947 IDA protein complex scaffold
GO:0043066 IEA:IDA negative regulation of apoptotic process
GO:0043154 IEA:IDA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043547 IDA positive regulation of GTPase activity
GO:0061462 IMP protein localization to lysosome
GO:0071230 IMP cellular response to amino acid stimulus
GO:0071986 IDA Ragulator complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000090194 lamtor5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 protein_coding Danio_rerio
ENSMUSG00000087260 Lamtor5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 protein_coding Mus_musculus

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