C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: spire-type actin nucleation factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000134278 SPIRE1 9606 - 18:12446512-12658134 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000309836 SPIRE1-005 12449504-12656732 protein_coding
  ENST00000409402 SPIRE1-001 12446512-12658134 protein_coding
  ENST00000410092 SPIRE1-002 12446513-12658045 protein_coding
  ENST00000440472 SPIRE1-003 12449506-12636340 nonsense_mediated_decay
  ENST00000449797 SPIRE1-006 12506496-12653085 protein_coding
  ENST00000453447 SPIRE1-010 12449509-12656736 protein_coding
  ENST00000462226 SPIRE1-004 12535478-12656720 protein_coding
  ENST00000464481 SPIRE1-008 12449666-12493149 processed_transcript
  ENST00000487491 SPIRE1-007 12493139-12516225 processed_transcript
  ENST00000497844 SPIRE1-011 12512513-12656728 protein_coding
  ENST00000498803 SPIRE1-009 12449573-12452610 retained_intron
  ENST00000588236 SPIRE1-013 12449810-12454506 retained_intron
  ENST00000592156 SPIRE1-012 12449668-12506519 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000409402ENST00000410092ENST00000449797ENST00000453447ENST00000498803
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000409402 N/A N/A 4.884±0.00 1.679±0.00 1.809±0.00 N/A N/A N/A N/A N/A 3.159±0.00 N/A N/A
ENST00000410092 3.843±0.00 3.240±0.00 11.984±3.16 4.278±0.00 2.104±0.00 6.175±3.25 7.141±0.00 5.359±3.22 7.304±0.36 19.845±0.00 3.643±1.56 2.352±0.00 20.514±9.28
ENST00000449797 N/A N/A N/A N/A N/A 6.053±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000453447 N/A N/A 7.429±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000498803 N/A 49.670±0.00 N/A N/A N/A N/A N/A N/A 50.495±0.00 21.173±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007ZP CIL_0007ZP_0001 VISTA 18:11977697-12581651
CIL_00010Z CIL_00010Z_0001 CGP 18:12407896-12658134

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003779 IEA actin binding
GO:0005794 IEA Golgi apparatus
GO:0005856 IEA cytoskeleton
GO:0005886 IEA plasma membrane
GO:0005938 ISS cell cortex
GO:0015031 IEA protein transport
GO:0016192 ISS vesicle-mediated transport
GO:0030036 IMP actin cytoskeleton organization
GO:0030659 ISS cytoplasmic vesicle membrane
GO:0032154 ISS cleavage furrow
GO:0036089 ISS cleavage furrow formation
GO:0040038 ISS polar body extrusion after meiotic divisions
GO:0046907 ISS intracellular transport
GO:0048193 IEA Golgi vesicle transport
GO:0051295 IMP establishment of meiotic spindle localization
GO:0070649 ISS formin-nucleated actin cable assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035868 spire1a spire homolog 1a (Drosophila) protein_coding Danio_rerio
ENSDARG00000038445 SPIRE1 (2 of 3) spire-type actin nucleation factor 1 protein_coding Danio_rerio
ENSDARG00000086693 CR524823.3 Uncharacterized protein protein_coding Danio_rerio
ENSMUSG00000024533 Spire1 spire homolog 1 (Drosophila) protein_coding Mus_musculus

Loading