C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: TAO kinase 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000135090 TAOK3 9606 - 12:118149801-118372945 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000392533 TAOK3-001 118149801-118372945 protein_coding
  ENST00000419821 TAOK3-002 118149801-118359720 protein_coding
  ENST00000535570 TAOK3-016 118238102-118256059 protein_coding
  ENST00000536584 TAOK3-005 118198390-118214171 retained_intron
  ENST00000536979 TAOK3-017 118150909-118152753 protein_coding
  ENST00000537305 TAOK3-004 118150443-118243490 retained_intron
  ENST00000537569 TAOK3-019 118159776-118161879 retained_intron
  ENST00000537822 TAOK3-007 118181515-118190551 protein_coding
  ENST00000537952 TAOK3-006 118150957-118190545 protein_coding
  ENST00000538601 TAOK3-003 118201422-118243448 protein_coding
  ENST00000539872 TAOK3-013 118255512-118359121 protein_coding
  ENST00000540561 TAOK3-008 118181442-118190522 protein_coding
  ENST00000541186 TAOK3-011 118243430-118359105 protein_coding
  ENST00000541786 TAOK3-014 118255504-118359676 protein_coding
  ENST00000541878 TAOK3-009 118244901-118359720 protein_coding
  ENST00000542532 TAOK3-012 118255460-118372889 protein_coding
  ENST00000542692 TAOK3-015 118255596-118372893 processed_transcript
  ENST00000542902 TAOK3-010 118244914-118359166 protein_coding
  ENST00000543709 TAOK3-018 118149942-118160358 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000392533ENST00000419821ENST00000537305ENST00000537952
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000392533 3.472±0.00 2.865±0.00 N/A 2.189±1.07 1.964±0.00 1.922±0.48 1.423±1.18 1.338±0.04 1.009±0.00 2.483±0.82 0.918±0.00 2.643±0.69 2.688±1.01 3.082±0.30
ENST00000419821 N/A N/A 0.607±0.00 N/A N/A 0.784±0.00 N/A N/A N/A 1.040±0.00 N/A 1.020±0.00 N/A N/A
ENST00000537305 N/A N/A 0.626±0.00 N/A N/A N/A 0.270±0.00 N/A 1.193±0.00 1.383±0.00 N/A N/A N/A N/A
ENST00000537952 N/A N/A N/A 5.191±0.66 1.775±0.00 N/A 0.690±0.00 1.081±0.00 3.766±0.00 2.094±0.00 0.718±0.00 6.916±2.98 3.776±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001QC CIL_0001QC_0002 CGP 12:118135858-118372945
CIL_0007G7 CIL_0007G7_0002 CGP 12:118149801-118418031

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000165 IMP MAPK cascade
GO:0004672 IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004860 TAS protein kinase inhibitor activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0006281 IEA DNA repair
GO:0006468 IEA:IDA protein phosphorylation
GO:0006469 TAS negative regulation of protein kinase activity
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0007095 IMP mitotic G2 DNA damage checkpoint
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0016740 IDA transferase activity
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0032874 IMP positive regulation of stress-activated MAPK cascade
GO:0043507 IMP positive regulation of JUN kinase activity
GO:0046329 IDA negative regulation of JNK cascade
GO:0046330 IMP positive regulation of JNK cascade
GO:0046777 IDA protein autophosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060751 taok3a TAO kinase 3a protein_coding Danio_rerio
ENSDARG00000094052 taok3b TAO kinase 3b protein_coding Danio_rerio
ENSMUSG00000061288 Taok3 TAO kinase 3 protein_coding Mus_musculus

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