C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: deltex 1, E3 ubiquitin ligase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000135144 DTX1 9606 + 12:113056709-113098028 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000257600 DTX1-001 113057690-113098028 protein_coding
  ENST00000547730 DTX1-004 113095040-113095623 processed_transcript
  ENST00000547974 DTX1-002 113089866-113097997 processed_transcript
  ENST00000548759 DTX1-005 113056709-113058152 processed_transcript
  ENST00000553140 DTX1-003 113093490-113094947 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000257600ENST00000547730ENST00000547974ENST00000548759ENST00000553140
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000257600 12.553±0.00 14.070±0.00 0.641±0.00 6.304±5.32 13.277±13.20 0.823±0.00 0.324±0.00 1.573±0.80 6.111±5.68 0.358±0.27 N/A 1.924±1.51 1.146±0.77 3.919±0.40
ENST00000547730 N/A N/A N/A N/A N/A N/A N/A N/A 1.067±0.00 N/A N/A N/A N/A N/A
ENST00000547974 6.219±0.00 12.878±0.00 N/A 0.965±0.00 N/A 0.276±0.00 N/A N/A 2.034±0.00 0.085±0.00 0.029±0.00 N/A 0.540±0.22 1.099±0.00
ENST00000548759 N/A N/A N/A N/A 0.406±0.00 N/A 0.041±0.00 N/A N/A 0.519±0.00 N/A N/A 1.021±0.43 N/A
ENST00000553140 N/A N/A N/A N/A N/A 0.718±0.00 0.459±0.00 N/A N/A N/A N/A 0.846±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005UQ CIL_0005UQ_0002 CGP 12:113056709-113136239

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003713 TAS transcription coactivator activity
GO:0005112 IDA Notch binding
GO:0005515 IPI:IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 TAS cytoplasm
GO:0005829 TAS cytosol
GO:0006351 NAS transcription, DNA-templated
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0007166 TAS cell surface receptor signaling pathway
GO:0007219 TAS Notch signaling pathway
GO:0008270 IEA zinc ion binding
GO:0008593 IGI regulation of Notch signaling pathway
GO:0010001 IEA glial cell differentiation
GO:0016567 IEA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0017124 IEA SH3 domain binding
GO:0031625 IPI ubiquitin protein ligase binding
GO:0045581 IEA negative regulation of T cell differentiation
GO:0045665 IGI negative regulation of neuron differentiation
GO:2001141 TAS regulation of RNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062840 DTX1 deltex 1, E3 ubiquitin ligase protein_coding Danio_rerio
ENSMUSG00000029603 Dtx1 deltex 1 homolog (Drosophila) protein_coding Mus_musculus

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