C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein kinase (cAMP-dependent, catalytic) inhibitor beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000135549 PKIB 9606 + 6:122471917-122726373 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000258014 PKIB-001 122652732-122726373 protein_coding
  ENST00000354275 PKIB-005 122717561-122725892 protein_coding
  ENST00000368446 PKIB-003 122717562-122725281 protein_coding
  ENST00000368448 PKIB-004 122610232-122725892 protein_coding
  ENST00000368452 PKIB-002 122610232-122725892 protein_coding
  ENST00000392490 PKIB-201 122610232-122726372 protein_coding
  ENST00000392491 PKIB-006 122471931-122725890 protein_coding
  ENST00000583007 PKIB-011 122482088-122633330 processed_transcript
  ENST00000607474 PKIB-008 122471934-122493475 processed_transcript
  ENST00000608895 PKIB-009 122471979-122586124 processed_transcript
  ENST00000615438 PKIB-202 122471917-122726372 protein_coding
  ENST00000618977 PKIB-010 122482079-122633330 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000258014ENST00000354275ENST00000368446ENST00000368452ENST00000392490ENST00000392491ENST00000607474ENST00000615438
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000258014 N/A 0.091±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.647±1.83 N/A
ENST00000354275 N/A 0.231±0.00 N/A 0.463±0.00 0.972±0.00 2.949±0.00 0.039±0.00 0.796±0.08 0.343±0.03 1.100±0.00 0.033±0.00 0.633±0.00 18.233±0.00 N/A
ENST00000368446 N/A N/A N/A N/A 0.641±0.00 N/A 0.070±0.00 N/A 0.357±0.22 N/A N/A 1.008±0.63 N/A N/A
ENST00000368452 0.435±0.00 N/A N/A 0.731±0.13 1.438±0.60 9.084±7.99 N/A N/A 0.463±0.00 1.750±0.00 N/A 0.330±0.08 20.139±3.59 0.717±0.03
ENST00000392490 0.073±0.00 N/A N/A 0.700±0.42 N/A 0.440±0.00 0.080±0.00 N/A N/A N/A N/A 0.060±0.01 N/A N/A
ENST00000392491 N/A N/A 0.226±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.624±0.58 N/A N/A
ENST00000607474 N/A N/A N/A N/A N/A N/A N/A 0.481±0.00 N/A N/A N/A N/A N/A N/A
ENST00000615438 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.176±0.06

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005OO CIL_0005OO_0001 CGP 6:122443354-122726373
CIL_0005OR CIL_0005OR_0001 CGP 6:122471917-122784074

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004862 IEA cAMP-dependent protein kinase inhibitor activity
GO:0006469 IEA negative regulation of protein kinase activity
GO:0071901 IEA negative regulation of protein serine/threonine kinase activity
GO:2000480 IEA negative regulation of cAMP-dependent protein kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000053110 pkib protein kinase (cAMP-dependent, catalytic) inhibitor beta protein_coding Danio_rerio
ENSMUSG00000019876 Pkib protein kinase inhibitor beta, cAMP dependent, testis specific protein_coding Mus_musculus

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