C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tec protein tyrosine kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000135605 TEC 9606 - 4:48135783-48269864 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000381501 TEC-001 48135783-48269864 protein_coding
  ENST00000505452 TEC-005 48136804-48228659 nonsense_mediated_decay
  ENST00000511150 TEC-017 48138916-48141683 retained_intron
  ENST00000511471 TEC-016 48141356-48155866 processed_transcript
  ENST00000515146 TEC-015 48137410-48146401 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000381501ENST00000505452ENST00000511471ENST00000515146
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000381501 0.300±0.00 0.421±0.00 N/A 0.074±0.00 0.300±0.00 N/A N/A 0.235±0.16 0.410±0.29 0.514±0.00 N/A 0.435±0.34 0.677±0.00 0.606±0.45
ENST00000505452 N/A N/A N/A N/A N/A 0.127±0.00 0.065±0.00 0.331±0.00 0.119±0.00 0.387±0.00 0.085±0.00 0.378±0.00 0.091±0.00 0.522±0.00
ENST00000511471 N/A N/A 0.523±0.00 N/A 0.360±0.00 N/A 0.125±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000515146 0.489±0.00 N/A 0.811±0.00 0.259±0.20 0.266±0.00 N/A 0.170±0.00 N/A N/A N/A N/A N/A 0.243±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001MY CIL_0001MY_0001 CGP 4:48066393-48269864
CIL_0001MX CIL_0001MX_0001 CGP 4:48135783-48426212

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004715 IDA non-membrane spanning protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005829 TAS cytosol
GO:0005856 IDA cytoskeleton
GO:0005886 IEA plasma membrane
GO:0005911 IEA cell-cell junction
GO:0006468 TAS:IEA protein phosphorylation
GO:0007229 IDA integrin-mediated signaling pathway
GO:0008289 IEA lipid binding
GO:0010543 IDA regulation of platelet activation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0035556 IEA intracellular signal transduction
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0042246 IEA tissue regeneration
GO:0045087 TAS innate immune response
GO:0046872 IEA metal ion binding
GO:0050853 IDA B cell receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000086680 tec tec protein tyrosine kinase protein_coding Danio_rerio
ENSMUSG00000029217 Tec tec protein tyrosine kinase protein_coding Mus_musculus

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