C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tec protein tyrosine kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029217 Tec 10090 - 5:72755718-72868483 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000071944 Tec-001 72755718-72868452 protein_coding
  ENSMUST00000073843 Tec-005 72755738-72868445 protein_coding
  ENSMUST00000113594 Tec-002 72755723-72868459 protein_coding
  ENSMUST00000126481 Tec-006 72755734-72868396 nonsense_mediated_decay
  ENSMUST00000138842 Tec-003 72755738-72868483 nonsense_mediated_decay
  ENSMUST00000149533 Tec-004 72773209-72868448 nonsense_mediated_decay
  ENSMUST00000150193 Tec-008 72823158-72868443 retained_intron
  ENSMUST00000155342 Tec-007 72755738-72786020 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000071944ENSMUST00000073843ENSMUST00000113594ENSMUST00000126481ENSMUST00000138842ENSMUST00000150193ENSMUST00000155342
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000071944 0.552±0.00 N/A 0.481±0.02 0.472±0.23 N/A N/A 0.891±0.00 N/A 1.141±0.26 N/A 0.334±0.09 1.835±0.55 8.173±3.54 0.112±0.00
ENSMUST00000073843 N/A 0.496±0.00 0.837±0.26 0.343±0.14 N/A N/A 0.835±0.30 1.168±0.52 1.132±0.53 0.769±0.00 0.541±0.34 1.482±0.41 2.593±0.23 0.210±0.00
ENSMUST00000113594 N/A N/A N/A N/A N/A 0.549±0.00 N/A N/A 0.672±0.00 N/A 0.613±0.00 0.795±0.00 N/A N/A
ENSMUST00000126481 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.045±0.00
ENSMUST00000138842 0.282±0.00 0.252±0.00 N/A 0.195±0.00 0.790±0.31 1.077±0.44 0.837±0.21 0.788±0.24 1.888±0.40 0.566±0.12 0.599±0.00 0.772±0.37 1.439±0.00 N/A
ENSMUST00000150193 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.143±0.00 11.290±4.30 N/A
ENSMUST00000155342 0.638±0.20 0.466±0.21 0.513±0.00 0.387±0.06 2.426±0.46 1.126±0.41 1.431±0.41 3.000±1.02 1.125±0.36 0.949±0.29 0.403±0.12 1.280±0.45 4.276±0.00 0.355±0.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008RD CIL_0008RD_0002 VISTA 5:72193972-72795406
CIL_0001MY CIL_0001MY_0002 CGP 5:72695978-72868483
CIL_0001MX CIL_0001MX_0002 CGP 5:72755718-72978829

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002376 IEA immune system process
GO:0004713 IEA protein tyrosine kinase activity
GO:0004715 IEA non-membrane spanning protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005829 TAS cytosol
GO:0005856 IEA cytoskeleton
GO:0005886 IEA plasma membrane
GO:0005911 IDA cell-cell junction
GO:0007229 IEA integrin-mediated signaling pathway
GO:0008289 IEA lipid binding
GO:0010543 IEA regulation of platelet activation
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0035556 IEA intracellular signal transduction
GO:0042246 IEA tissue regeneration
GO:0046872 IEA metal ion binding
GO:0050853 IEA B cell receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000086680 tec tec protein tyrosine kinase protein_coding Danio_rerio
ENSG00000135605 TEC tec protein tyrosine kinase protein_coding Homo_sapiens

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