C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dedicator of cytokinesis 10
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000135905 DOCK10 9606 - 2:224765090-225042445 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000258390 DOCK10-001 224765090-225042442 protein_coding
  ENST00000409592 DOCK10-002 224765090-224947065 protein_coding
  ENST00000422684 DOCK10-006 224800162-224816652 protein_coding
  ENST00000435582 DOCK10-010 224893548-225042445 nonsense_mediated_decay
  ENST00000458608 DOCK10-011 224983415-225042384 nonsense_mediated_decay
  ENST00000471810 DOCK10-008 224886081-224982303 processed_transcript
  ENST00000472652 DOCK10-004 224837729-224840205 retained_intron
  ENST00000474102 DOCK10-009 224893342-224946905 processed_transcript
  ENST00000489831 DOCK10-005 224807245-224807933 retained_intron
  ENST00000492251 DOCK10-007 224792974-224795126 retained_intron
  ENST00000492369 DOCK10-012 224860580-225042442 retained_intron
  ENST00000535663 DOCK10-014 224773241-224787118 protein_coding
  ENST00000543715 DOCK10-013 224874700-224886254 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000258390ENST00000409592ENST00000422684ENST00000492369
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000258390 1.159±0.00 N/A 2.064±0.62 0.485±0.00 0.539±0.00 N/A 0.607±0.00 N/A 0.162±0.00 N/A 1.158±0.00 N/A 0.518±0.00
ENST00000409592 1.191±0.00 N/A N/A 2.952±0.00 0.955±0.00 0.139±0.00 0.665±0.00 1.322±0.00 4.495±0.00 N/A N/A 0.196±0.05 N/A
ENST00000422684 N/A N/A 7.709±0.00 N/A N/A N/A N/A N/A N/A 0.533±0.00 N/A 0.285±0.00 N/A
ENST00000492369 N/A 0.320±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006XM CIL_0006XM_0001 CGP 2:224470150-225042445
CIL_0006XS CIL_0006XS_0001 CGP 2:224765090-225654018

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003674 ND molecular_function
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005488 IEA binding
GO:0007264 IEA small GTPase mediated signal transduction
GO:0016020 IDA membrane
GO:0017048 IEA Rho GTPase binding
GO:0030334 IDA regulation of cell migration
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0043547 IEA positive regulation of GTPase activity
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075327 dock10 dedicator of cytokinesis 10 protein_coding Danio_rerio
ENSMUSG00000038608 Dock10 dedicator of cytokinesis 10 protein_coding Mus_musculus

Loading