C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dedicator of cytokinesis 10
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000038608 Dock10 10090 - 1:80501073-80758527 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000077946 Dock10-001 80501073-80758448 protein_coding
  ENSMUST00000186087 Dock10-005 80586330-80709496 protein_coding
  ENSMUST00000186835 Dock10-010 80502891-80506310 retained_intron
  ENSMUST00000187698 Dock10-002 80645706-80758487 retained_intron
  ENSMUST00000187774 Dock10-006 80501553-80665309 protein_coding
  ENSMUST00000187885 Dock10-012 80520498-80522396 retained_intron
  ENSMUST00000189486 Dock10-009 80501641-80530165 protein_coding
  ENSMUST00000190595 Dock10-011 80501188-80592832 protein_coding
  ENSMUST00000190983 Dock10-007 80501713-80665275 protein_coding
  ENSMUST00000191449 Dock10-008 80592601-80665292 protein_coding
  ENSMUST00000191505 Dock10-004 80583217-80758527 retained_intron

Mus musculus EnsemblGRCm38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000077946ENSMUST00000186087ENSMUST00000186835ENSMUST00000187774ENSMUST00000189486ENSMUST00000190595ENSMUST00000190983ENSMUST00000191505
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000077946 N/A 0.407±0.00 2.715±0.00 0.679±0.49 N/A N/A N/A N/A 1.112±0.68 N/A 0.192±0.04 0.499±0.00 0.162±0.10 N/A
ENSMUST00000186087 N/A N/A N/A N/A N/A N/A N/A 1.029±0.00 N/A N/A N/A 0.743±0.00 N/A N/A
ENSMUST00000186835 1.560±0.34 1.015±0.11 N/A N/A 5.359±1.55 0.683±0.11 N/A 0.652±0.32 0.158±0.05 3.881±0.56 0.099±0.00 0.578±0.27 N/A 0.051±0.03
ENSMUST00000187774 0.828±0.14 1.055±0.00 N/A 1.136±0.00 2.983±1.70 0.464±0.00 0.370±0.13 0.218±0.00 0.263±0.15 N/A N/A 0.502±0.18 0.039±0.01 0.050±0.02
ENSMUST00000189486 N/A N/A N/A 0.379±0.00 N/A 0.407±0.12 N/A N/A 0.507±0.39 N/A 0.155±0.02 0.649±0.20 0.140±0.10 0.109±0.00
ENSMUST00000190595 0.930±0.00 0.664±0.00 N/A 1.477±1.23 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.042±0.00
ENSMUST00000190983 N/A N/A N/A 1.124±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.090±0.00 N/A
ENSMUST00000191505 N/A 1.291±0.23 N/A N/A N/A N/A N/A N/A 0.105±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006XM CIL_0006XM_0002 CGP 1:80264923-80758527
CIL_0006XS CIL_0006XS_0002 CGP 1:80501073-81341764

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005089 IDA Rho guanyl-nucleotide exchange factor activity
GO:0007264 IEA small GTPase mediated signal transduction
GO:0016020 IEA membrane
GO:0017048 IPI Rho GTPase binding
GO:0030334 IEA regulation of cell migration
GO:0032321 IDA positive regulation of Rho GTPase activity
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075327 dock10 dedicator of cytokinesis 10 protein_coding Danio_rerio
ENSG00000135905 DOCK10 dedicator of cytokinesis 10 protein_coding Homo_sapiens

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