C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: eukaryotic translation initiation factor 4E family member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000135930 EIF4E2 9606 + 2:232550052-232583644 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000258416 EIF4E2-001 232550052-232569210 protein_coding
  ENST00000409098 EIF4E2-002 232550683-232583644 protein_coding
  ENST00000409167 EIF4E2-005 232550689-232568020 protein_coding
  ENST00000409322 EIF4E2-014 232550692-232569178 protein_coding
  ENST00000409394 EIF4E2-008 232550704-232580956 protein_coding
  ENST00000409495 EIF4E2-007 232550689-232567527 protein_coding
  ENST00000409514 EIF4E2-003 232550683-232583642 protein_coding
  ENST00000444113 EIF4E2-013 232574074-232581332 protein_coding
  ENST00000454501 EIF4E2-010 232550807-232567205 protein_coding
  ENST00000459714 EIF4E2-012 232573721-232581062 processed_transcript
  ENST00000463074 EIF4E2-006 232550674-232556596 retained_intron
  ENST00000478878 EIF4E2-011 232566944-232569833 processed_transcript
  ENST00000479834 EIF4E2-009 232550806-232557648 processed_transcript
  ENST00000498242 EIF4E2-004 232550691-232558824 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000258416ENST00000409098ENST00000409322ENST00000409495ENST00000409514ENST00000454501ENST00000463074ENST00000498242
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000258416 N/A N/A N/A N/A N/A 3.064±0.00 N/A 2.650±0.00 4.666±3.06 N/A N/A 10.444±5.87 15.841±2.45 13.189±0.00
ENST00000409098 N/A 3.679±0.00 2.821±0.00 N/A N/A N/A 2.248±0.00 2.650±0.58 2.362±1.31 2.633±0.20 N/A 2.428±0.59 N/A 6.622±2.03
ENST00000409322 15.167±0.00 12.385±0.00 6.364±0.00 N/A 11.484±4.56 15.363±10.59 1.191±0.00 10.470±0.00 14.719±11.71 14.762±7.13 4.651±0.00 18.173±8.26 34.305±9.67 N/A
ENST00000409495 10.093±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 22.409±0.00 26.193±0.00 N/A
ENST00000409514 4.773±0.00 2.430±0.00 N/A 6.638±1.97 4.723±2.87 4.222±3.19 2.383±1.72 8.860±0.00 1.225±0.00 2.161±0.00 2.704±1.08 4.714±0.14 2.787±0.00 5.953±0.00
ENST00000454501 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 15.032±0.00 N/A N/A 25.669±7.65
ENST00000463074 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 25.694±0.00 N/A
ENST00000498242 N/A N/A N/A N/A N/A N/A 1.957±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003HV CIL_0003HV_0001 CGP 2:232550052-232682781

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000339 TAS RNA cap binding
GO:0001701 IEA in utero embryonic development
GO:0003723 IEA RNA binding
GO:0003743 IEA translation initiation factor activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0005845 IDA mRNA cap binding complex
GO:0006413 IEA translational initiation
GO:0008135 TAS translation factor activity, nucleic acid binding
GO:0017148 IMP negative regulation of translation
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0031625 IPI ubiquitin protein ligase binding
GO:0044822 IDA poly(A) RNA binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038585 eif4e2 eukaryotic translation initiation factor 4E family member 2 protein_coding Danio_rerio
ENSMUSG00000026254 Eif4e2 eukaryotic translation initiation factor 4E member 2 protein_coding Mus_musculus

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