C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: folylpolyglutamate synthase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000136877 FPGS 9606 + 9:127794597-127814327 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000373225 FPGS-012 127803208-127814059 protein_coding
  ENST00000373228 FPGS-017 127802911-127813424 protein_coding
  ENST00000373247 FPGS-011 127802875-127814069 protein_coding
  ENST00000393706 FPGS-201 127802858-127814081 protein_coding
  ENST00000423577 FPGS-001 127803324-127808301 protein_coding
  ENST00000431857 FPGS-020 127803252-127809715 protein_coding
  ENST00000460181 FPGS-014 127802918-127814058 processed_transcript
  ENST00000467826 FPGS-007 127808264-127814327 processed_transcript
  ENST00000469310 FPGS-002 127804286-127804857 processed_transcript
  ENST00000473536 FPGS-008 127808722-127810058 processed_transcript
  ENST00000475270 FPGS-009 127809994-127813574 processed_transcript
  ENST00000475765 FPGS-018 127802932-127807849 processed_transcript
  ENST00000479147 FPGS-015 127794597-127807682 processed_transcript
  ENST00000479375 FPGS-013 127794682-127808301 processed_transcript
  ENST00000481552 FPGS-003 127802917-127807688 processed_transcript
  ENST00000488307 FPGS-016 127802893-127808882 processed_transcript
  ENST00000488506 FPGS-006 127807673-127813284 processed_transcript
  ENST00000489522 FPGS-005 127808147-127810037 processed_transcript
  ENST00000496586 FPGS-019 127803024-127807279 processed_transcript
  ENST00000497386 FPGS-004 127806497-127808705 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000373225ENST00000373247ENST00000393706ENST00000423577ENST00000431857ENST00000460181ENST00000467826ENST00000481552ENST00000488307ENST00000489522ENST00000496586ENST00000497386
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000373225 7.714±0.00 N/A N/A 2.054±1.79 9.621±0.00 N/A N/A 1.190±0.00 0.353±0.00 N/A N/A N/A 3.536±0.31 4.735±0.68
ENST00000373247 17.463±0.00 N/A N/A 0.272±0.00 10.319±0.00 2.435±2.00 5.779±0.00 6.457±0.00 10.348±9.73 21.367±0.00 12.663±0.00 32.725±20.46 7.292±2.64 N/A
ENST00000393706 N/A N/A N/A N/A N/A N/A 0.241±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000423577 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 12.491±0.00 N/A N/A
ENST00000431857 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.883±0.00 N/A
ENST00000460181 N/A 26.424±0.00 N/A 1.308±0.99 8.325±0.00 N/A 2.453±0.00 4.030±0.00 N/A N/A 7.740±0.00 1.409±0.00 5.221±0.00 5.660±0.93
ENST00000467826 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.232±0.00 N/A N/A N/A N/A
ENST00000481552 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.804±0.00 N/A N/A N/A N/A
ENST00000488307 N/A N/A 0.637±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000489522 N/A N/A N/A 1.807±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000496586 N/A N/A N/A N/A N/A 2.068±0.00 N/A N/A N/A 2.204±0.00 N/A 2.483±0.00 N/A N/A
ENST00000497386 N/A N/A 0.781±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 5.595±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008YA CIL_0008YA_0001 VISTA 9:127227593-127829012

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001889 IEA liver development
GO:0004326 IEA tetrahydrofolylpolyglutamate synthase activity
GO:0005524 IEA ATP binding
GO:0005737 TAS cytoplasm
GO:0005739 TAS mitochondrion
GO:0005743 IEA mitochondrial inner membrane
GO:0005759 TAS mitochondrial matrix
GO:0005829 TAS cytosol
GO:0006139 TAS nucleobase-containing compound metabolic process
GO:0006730 IEA one-carbon metabolic process
GO:0006766 TAS vitamin metabolic process
GO:0006767 TAS water-soluble vitamin metabolic process
GO:0007420 IEA brain development
GO:0009058 IEA biosynthetic process
GO:0009396 IEA folic acid-containing compound biosynthetic process
GO:0016874 IEA ligase activity
GO:0031100 IEA organ regeneration
GO:0044281 TAS small molecule metabolic process
GO:0046655 TAS folic acid metabolic process
GO:0046901 IEA tetrahydrofolylpolyglutamate biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044809 fpgs folylpolyglutamate synthase protein_coding Danio_rerio
ENSMUSG00000009566 Fpgs folylpolyglutamyl synthetase protein_coding Mus_musculus

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