C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interleukin 33
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000137033 IL33 9606 + 9:6215786-6257983 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000381434 IL33-001 6241682-6257983 protein_coding
  ENST00000417746 IL33-201 6215786-6257982 protein_coding
  ENST00000456383 IL33-202 6241695-6257982 protein_coding
  ENST00000463336 IL33-002 6241693-6242734 processed_transcript
  ENST00000611532 IL33-203 6241680-6256223 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000381434ENST00000417746ENST00000456383ENST00000611532
Transcript ID Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000381434 24.076±0.00 N/A 2.736±1.97 N/A 1.755±0.93 N/A 2.995±0.93 18.274±0.00 0.505±0.31 1.368±0.99 6.900±1.54 3.425±1.08
ENST00000417746 9.415±0.00 N/A 3.368±0.00 N/A N/A 2.252±0.00 1.882±1.04 2.182±0.00 N/A 0.942±0.00 N/A N/A
ENST00000456383 7.898±0.00 0.518±0.00 N/A 3.698±0.00 0.934±0.00 0.214±0.00 1.298±0.00 5.417±0.00 N/A 1.991±0.00 N/A N/A
ENST00000611532 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.499±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001DB CIL_0001DB_0001 CGP 9:6011043-6257983
CIL_00011Y CIL_00011Y_0001 CGP 9:6215786-6331900

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002686 IEA negative regulation of leukocyte migration
GO:0002826 IEA negative regulation of T-helper 1 type immune response
GO:0002830 IEA positive regulation of type 2 immune response
GO:0005125 IDA cytokine activity
GO:0005515 IPI protein binding
GO:0005615 IEA extracellular space
GO:0005634 IEA nucleus
GO:0005694 IEA chromosome
GO:0006351 IEA transcription, DNA-templated
GO:0010628 IEA positive regulation of gene expression
GO:0031410 IEA cytoplasmic vesicle
GO:0032436 IEA positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032689 IEA negative regulation of interferon-gamma production
GO:0032736 IEA positive regulation of interleukin-13 production
GO:0032753 IEA positive regulation of interleukin-4 production
GO:0032754 IEA positive regulation of interleukin-5 production
GO:0032755 IEA positive regulation of interleukin-6 production
GO:0043032 IDA positive regulation of macrophage activation
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0050729 ISS positive regulation of inflammatory response
GO:0051024 IEA positive regulation of immunoglobulin secretion
GO:0051025 IEA negative regulation of immunoglobulin secretion
GO:0090197 IDA positive regulation of chemokine secretion
GO:0097191 IEA extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000024810 Il33 interleukin 33 protein_coding Mus_musculus

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