C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interleukin 33
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024810 Il33 10090 + 19:29925114-29960718 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025724 Il33-002 29945790-29960704 protein_coding
  ENSMUST00000120388 Il33-001 29925114-29960718 protein_coding
  ENSMUST00000136850 Il33-004 29951816-29952813 protein_coding
  ENSMUST00000144528 Il33-003 29925115-29952077 protein_coding
  ENSMUST00000177518 Il33-005 29925132-29958975 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025724ENSMUST00000120388ENSMUST00000177518
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025724 N/A N/A 0.960±0.00 0.069±0.00 3.945±0.00 1.181±0.00 N/A 0.855±0.26 0.265±0.19 N/A 0.189±0.00 0.860±0.50 0.263±0.24 0.399±0.09
ENSMUST00000120388 2.223±0.61 3.714±0.43 9.160±1.90 0.630±0.72 10.562±3.76 1.977±0.47 1.546±0.44 3.863±1.03 0.784±0.41 36.230±0.60 0.782±0.37 4.267±1.79 0.430±0.55 1.141±0.26
ENSMUST00000177518 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.038±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001DB CIL_0001DB_0002 CGP 19:29808108-29960718
CIL_00011Y CIL_00011Y_0002 CGP 19:29925114-30006020

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002686 IGI negative regulation of leukocyte migration
GO:0002826 IGI negative regulation of T-helper 1 type immune response
GO:0002830 IGI positive regulation of type 2 immune response
GO:0005125 IPI cytokine activity
GO:0005515 IEA protein binding
GO:0005615 IEA extracellular space
GO:0005634 ISO nucleus
GO:0005694 IEA chromosome
GO:0006351 IEA transcription, DNA-templated
GO:0010628 IDA positive regulation of gene expression
GO:0031410 IEA cytoplasmic vesicle
GO:0032436 IDA positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032689 IGI negative regulation of interferon-gamma production
GO:0032736 IGI positive regulation of interleukin-13 production
GO:0032753 IGI positive regulation of interleukin-4 production
GO:0032754 IGI positive regulation of interleukin-5 production
GO:0032755 IGI positive regulation of interleukin-6 production
GO:0043032 IDA positive regulation of macrophage activation
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0050729 IDA positive regulation of inflammatory response
GO:0051024 IGI positive regulation of immunoglobulin secretion
GO:0051025 IGI negative regulation of immunoglobulin secretion
GO:0090197 IDA positive regulation of chemokine secretion
GO:0097191 IGI extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000137033 IL33 interleukin 33 protein_coding Homo_sapiens

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