C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: signaling threshold regulating transmembrane adaptor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000137078 SIT1 9606 - 9:35649295-35650950 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000259608 SIT1-001 35649295-35650940 protein_coding
  ENST00000474403 SIT1-002 35649427-35650910 processed_transcript
  ENST00000486859 SIT1-003 35649368-35650470 processed_transcript
  ENST00000618781 SIT1-201 35649303-35650950 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000259608ENST00000474403ENST00000486859ENST00000618781
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000259608 N/A 12.083±0.00 N/A 0.291±0.00 0.087±0.04 0.098±0.00 0.166±0.00 0.130±0.00 N/A 0.695±0.15 0.273±0.05 0.166±0.10
ENST00000474403 0.078±0.00 4.889±0.00 0.034±0.00 0.241±0.00 0.322±0.00 N/A N/A N/A 1.254±0.00 0.437±0.11 0.262±0.11 0.054±0.00
ENST00000486859 N/A N/A N/A 0.268±0.11 0.070±0.00 N/A 0.213±0.00 0.228±0.00 0.420±0.00 0.318±0.00 0.175±0.00 0.062±0.00
ENST00000618781 0.154±0.00 N/A N/A N/A N/A N/A N/A N/A 1.200±0.00 0.266±0.00 0.305±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00072P CIL_00072P_0001 CGP 9:35609533-35650950
CIL_00072Q CIL_00072Q_0001 CGP 9:35649295-35661511

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002376 IEA immune system process
GO:0005515 IPI protein binding
GO:0005886 IDA plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0007165 TAS signal transduction
GO:0019900 IPI kinase binding
GO:0042169 TAS SH2 domain binding
GO:0050863 IDA regulation of T cell activation
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000028460 Sit1 suppression inducing transmembrane adaptor 1 protein_coding Mus_musculus

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