C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000137492 PRKRIR 9606 - 11:76349956-76380971 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000260045 PRKRIR-001 76349956-76380942 protein_coding
  ENST00000525277 PRKRIR-005 76352625-76361369 retained_intron
  ENST00000528993 PRKRIR-003 76352498-76380971 nonsense_mediated_decay
  ENST00000529901 PRKRIR-002 76349956-76359573 retained_intron
  ENST00000531878 PRKRIR-004 76352697-76368643 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000260045ENST00000531878
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000260045 3.915±0.00 6.144±0.00 2.852±0.00 2.338±0.26 4.108±1.16 4.776±0.13 1.739±0.58 3.450±1.39 1.962±0.31 3.527±0.28 2.267±0.00 7.089±1.80 8.449±2.09 8.353±1.53
ENST00000531878 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.840±0.00 8.581±0.00 8.683±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003676 IEA nucleic acid binding
GO:0003677 IEA DNA binding
GO:0005634 IEA nucleus
GO:0006950 TAS response to stress
GO:0007165 TAS signal transduction
GO:0008285 TAS negative regulation of cell proliferation
GO:0046872 IEA metal ion binding
GO:0046983 IEA protein dimerization activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020964 prkrirb protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) b protein_coding Danio_rerio
ENSDARG00000042489 prkrira protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) a protein_coding Danio_rerio
ENSMUSG00000030753 Prkrir protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) protein_coding Mus_musculus

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