C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NIMA-related kinase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000137601 NEK1 9606 - 4:169393275-169612629 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000439128 NEK1-001 169393275-169612612 protein_coding
  ENST00000505119 NEK1-008 169576604-169585499 protein_coding
  ENST00000507142 NEK1-004 169393395-169612629 protein_coding
  ENST00000509912 NEK1-007 169554043-169599143 retained_intron
  ENST00000510108 NEK1-006 169585349-169612581 nonsense_mediated_decay
  ENST00000510533 NEK1-002 169393390-169612583 protein_coding
  ENST00000511633 NEK1-003 169393281-169612627 protein_coding
  ENST00000512193 NEK1-005 169394228-169612627 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000439128ENST00000507142ENST00000509912ENST00000510533ENST00000511633ENST00000512193
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000439128 N/A N/A 1.269±0.00 N/A N/A N/A 0.651±0.00 0.269±0.00 N/A N/A 0.654±0.21 N/A 1.271±0.00
ENST00000507142 N/A N/A 0.631±0.20 0.294±0.00 N/A 1.119±0.00 N/A N/A N/A 0.722±0.00 N/A 1.477±0.00 N/A
ENST00000509912 0.380±0.00 N/A N/A N/A 0.703±0.00 0.541±0.00 0.862±0.00 0.089±0.00 1.034±0.00 N/A N/A 0.719±0.60 N/A
ENST00000510533 0.218±0.00 N/A N/A N/A N/A 0.429±0.00 N/A N/A 0.903±0.00 0.833±0.00 0.759±0.16 0.851±0.60 3.606±0.00
ENST00000511633 N/A N/A N/A N/A 0.453±0.00 0.548±0.02 N/A N/A 0.972±0.64 N/A 0.715±0.14 0.244±0.00 N/A
ENST00000512193 N/A 1.066±0.00 N/A 0.596±0.00 N/A 0.347±0.00 N/A 0.542±0.00 0.439±0.00 N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000242 IDA pericentriolar material
GO:0004672 IDA:IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005813 IDA centrosome
GO:0006468 IEA protein phosphorylation
GO:0006974 IEA cellular response to DNA damage stimulus
GO:0007067 IEA mitotic nuclear division
GO:0010212 IEA response to ionizing radiation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0042384 IMP cilium assembly
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000022350 nek1 NIMA (never in mitosis gene a)-related kinase 1 protein_coding Danio_rerio
ENSMUSG00000031644 Nek1 NIMA (never in mitosis gene a)-related expressed kinase 1 protein_coding Mus_musculus

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