C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NIMA (never in mitosis gene a)-related expressed kinase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031644 Nek1 10090 + 8:60993195-61131346 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000034065 Nek1-001 60993195-61131346 protein_coding
  ENSMUST00000120689 Nek1-002 60993195-61131339 protein_coding
  ENSMUST00000125717 Nek1-006 60993200-61044543 retained_intron
  ENSMUST00000140444 Nek1-004 60993241-61030059 retained_intron
  ENSMUST00000142601 Nek1-007 61049835-61089455 protein_coding
  ENSMUST00000154313 Nek1-005 60993241-61030600 retained_intron
  ENSMUST00000155664 Nek1-003 60993239-61107351 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000034065ENSMUST00000120689ENSMUST00000125717ENSMUST00000142601ENSMUST00000155664
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000034065 0.740±0.36 N/A 2.423±0.74 3.999±1.52 0.460±0.26 0.574±0.19 0.498±0.17 0.509±0.30 1.379±0.95 1.117±0.26 0.583±0.16 2.530±1.97 1.517±0.57 5.731±2.18
ENSMUST00000120689 0.550±0.06 N/A 0.685±0.12 2.360±1.67 0.315±0.07 N/A 0.304±0.10 0.508±0.00 0.540±0.07 0.730±0.00 0.450±0.14 4.487±0.00 1.020±0.65 N/A
ENSMUST00000125717 2.569±1.35 16.717±0.73 N/A N/A 9.825±4.59 6.112±0.49 0.966±0.00 1.984±0.79 1.476±0.66 7.568±1.60 N/A 15.469±3.49 N/A 4.321±1.37
ENSMUST00000142601 N/A N/A N/A 14.022±0.00 N/A N/A N/A N/A N/A N/A N/A 12.027±0.00 6.922±1.53 N/A
ENSMUST00000155664 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 11.139±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006KO CIL_0006KO_0002 CGP 8:60993195-61396072

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000242 IEA pericentriolar material
GO:0004672 ISA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 ISA nucleus
GO:0005737 ISA cytoplasm
GO:0005813 IDA centrosome
GO:0006468 IEA protein phosphorylation
GO:0006974 IMP cellular response to DNA damage stimulus
GO:0007067 IEA mitotic nuclear division
GO:0010212 IMP response to ionizing radiation
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0042384 IEA cilium assembly
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000022350 nek1 NIMA (never in mitosis gene a)-related kinase 1 protein_coding Danio_rerio
ENSG00000137601 NEK1 NIMA-related kinase 1 protein_coding Homo_sapiens

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