C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: POU class 2 homeobox 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000137709 POU2F3 9606 + 11:120236640-120319944 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000260264 POU2F3-006 120236640-120319944 protein_coding
  ENST00000529039 POU2F3-004 120317166-120319187 retained_intron
  ENST00000532638 POU2F3-003 120305488-120319331 retained_intron
  ENST00000532663 POU2F3-005 120305644-120317364 protein_coding
  ENST00000533620 POU2F3-002 120240261-120318439 nonsense_mediated_decay
  ENST00000543440 POU2F3-001 120240194-120318884 protein_coding
  ENST00000606153 POU2F3-007 120300903-120304330 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000260264ENST00000529039ENST00000532638ENST00000532663ENST00000533620ENST00000543440ENST00000606153
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000260264 N/A 0.062±0.00 N/A 0.042±0.00 N/A N/A 0.025±0.00 N/A 0.011±0.00 N/A N/A 0.067±0.00 0.152±0.02 N/A
ENST00000529039 N/A N/A 0.149±0.00 N/A 0.127±0.00 0.550±0.00 N/A 0.070±0.00 N/A 0.302±0.00 N/A 0.200±0.13 1.012±0.62 0.350±0.00
ENST00000532638 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.040±0.00 0.161±0.08 N/A
ENST00000532663 N/A N/A N/A N/A N/A 0.215±0.00 N/A N/A 0.067±0.00 0.889±0.00 0.596±0.00 0.171±0.00 N/A N/A
ENST00000533620 0.068±0.00 N/A N/A N/A 0.119±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000543440 0.029±0.00 N/A N/A N/A 0.048±0.00 0.071±0.00 N/A N/A N/A 0.313±0.00 N/A 0.430±0.00 N/A N/A
ENST00000606153 0.045±0.00 N/A N/A N/A 0.068±0.00 N/A 0.012±0.00 N/A 0.028±0.02 0.108±0.00 0.004±0.00 N/A 0.038±0.00 0.022±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00021Y CIL_00021Y_0002 CGP 11:120210767-120319944

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000978 IMP RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IEA transcription factor complex
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 TAS regulation of transcription from RNA polymerase II promoter
GO:0008544 TAS epidermis development
GO:0030216 IEA keratinocyte differentiation
GO:0042060 IEA wound healing
GO:0043565 IDA sequence-specific DNA binding
GO:0043922 IDA negative regulation by host of viral transcription
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046983 IEA protein dimerization activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052387 pou2f3 POU class 2 homeobox 3 protein_coding Danio_rerio
ENSMUSG00000032015 Pou2f3 POU domain, class 2, transcription factor 3 protein_coding Mus_musculus

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