C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: p21 protein (Cdc42/Rac)-activated kinase 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000137843 PAK6 9606 + 15:40238759-40277487 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000260404 PAK6-001 40239870-40277487 protein_coding
  ENST00000455577 PAK6-002 40239091-40277486 protein_coding
  ENST00000542403 PAK6-004 40253184-40277487 protein_coding
  ENST00000557808 PAK6-016 40273930-40276384 retained_intron
  ENST00000557926 PAK6-017 40266612-40272354 processed_transcript
  ENST00000558055 PAK6-006 40239054-40266003 protein_coding
  ENST00000558106 PAK6-011 40252190-40266006 protein_coding
  ENST00000558183 PAK6-008 40240567-40264989 protein_coding
  ENST00000558878 PAK6-007 40240522-40264940 protein_coding
  ENST00000559139 PAK6-013 40252888-40265964 protein_coding
  ENST00000559617 PAK6-010 40252548-40265974 protein_coding
  ENST00000559901 PAK6-015 40266014-40266982 processed_transcript
  ENST00000560346 PAK6-003 40239420-40277485 protein_coding
  ENST00000560669 PAK6-014 40253003-40266491 protein_coding
  ENST00000560684 PAK6-012 40252551-40264980 protein_coding
  ENST00000560806 PAK6-009 40240645-40264827 protein_coding
  ENST00000561230 PAK6-005 40238759-40265951 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainHeartKidneyLiverLungOvaryPlacentaTestisENST00000260404ENST00000455577ENST00000542403ENST00000558106ENST00000560346ENST00000561230
Transcript ID Adipose Bladder Brain Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000260404 0.145±0.00 N/A 2.295±0.00 0.830±0.00 0.913±0.00 N/A 0.419±0.00 N/A N/A 9.671±0.00
ENST00000455577 N/A N/A N/A N/A N/A 0.039±0.00 N/A N/A N/A N/A
ENST00000542403 N/A N/A N/A 0.044±0.00 N/A N/A N/A 0.972±0.00 1.067±0.00 N/A
ENST00000558106 N/A N/A N/A N/A N/A 0.420±0.00 N/A N/A N/A N/A
ENST00000560346 N/A 0.145±0.00 3.327±0.67 N/A 1.939±0.00 0.071±0.00 N/A N/A N/A N/A
ENST00000561230 N/A 1.018±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008W0 CIL_0008W0_0001 VISTA 15:39791359-40393937
CIL_0005IH CIL_0005IH_0002 CGP 15:40161023-40277486

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006355 TAS regulation of transcription, DNA-templated
GO:0006468 IEA protein phosphorylation
GO:0006915 TAS apoptotic process
GO:0007010 TAS cytoskeleton organization
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027564 protein_coding Danio_rerio
ENSDARG00000052405 pak6b p21 protein (Cdc42/Rac)-activated kinase 6b protein_coding Danio_rerio
ENSMUSG00000074923 Pak6 p21 protein (Cdc42/Rac)-activated kinase 6 protein_coding Mus_musculus

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