C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytochrome P450, family 19, subfamily A, polypeptide 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000137869 CYP19A1 9606 - 15:51208057-51338610 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000260433 CYP19A1-201 51208058-51323924 protein_coding
  ENST00000396402 CYP19A1-001 51208057-51338610 protein_coding
  ENST00000396404 CYP19A1-007 51210181-51338596 protein_coding
  ENST00000405011 CYP19A1-013 51222479-51338597 protein_coding
  ENST00000405913 CYP19A1-004 51221379-51243011 protein_coding
  ENST00000439712 CYP19A1-011 51212527-51338598 non_stop_decay
  ENST00000453807 CYP19A1-008 51218558-51338601 protein_coding
  ENST00000478421 CYP19A1-006 51215787-51218548 processed_transcript
  ENST00000490076 CYP19A1-005 51210981-51215987 retained_intron
  ENST00000492852 CYP19A1-003 51312227-51338581 processed_transcript
  ENST00000557858 CYP19A1-016 51222264-51338575 protein_coding
  ENST00000557934 CYP19A1-009 51212527-51338596 non_stop_decay
  ENST00000558066 CYP19A1-019 51215032-51222354 retained_intron
  ENST00000558328 CYP19A1-015 51215711-51338580 protein_coding
  ENST00000559646 CYP19A1-012 51222483-51318492 protein_coding
  ENST00000559653 CYP19A1-020 51212259-51215224 protein_coding
  ENST00000559878 CYP19A1-014 51210514-51243064 protein_coding
  ENST00000559980 CYP19A1-002 51222461-51338598 protein_coding
  ENST00000561066 CYP19A1-018 51277136-51278160 processed_transcript
  ENST00000561075 CYP19A1-017 51215182-51338596 protein_coding
  ENST00000613097 CYP19A1-202 51215787-51218548 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000260433ENST00000396402ENST00000396404ENST00000492852ENST00000557858ENST00000557934ENST00000558066ENST00000559646ENST00000559878ENST00000561066ENST00000561075
Transcript ID Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000260433 N/A 0.009±0.00 N/A 0.133±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000396402 N/A N/A 0.029±0.00 0.068±0.00 0.008±0.00 0.076±0.00 N/A N/A N/A 0.756±0.00 16.447±0.00 N/A
ENST00000396404 0.395±0.00 N/A N/A 0.155±0.00 0.022±0.00 N/A N/A N/A N/A 4.047±0.00 N/A N/A
ENST00000492852 N/A N/A N/A 0.253±0.00 0.025±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000557858 N/A 0.113±0.00 N/A N/A 0.260±0.00 N/A 0.223±0.00 N/A N/A N/A N/A N/A
ENST00000557934 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 40.127±0.00 N/A
ENST00000558066 N/A N/A N/A N/A 0.089±0.00 0.274±0.00 N/A 0.211±0.00 N/A N/A 57.472±0.00 N/A
ENST00000559646 N/A 0.250±0.20 N/A N/A 0.133±0.00 0.171±0.00 N/A 0.066±0.00 0.213±0.00 N/A N/A N/A
ENST00000559878 N/A 0.026±0.00 0.038±0.00 N/A 0.037±0.00 N/A N/A N/A N/A 2.202±0.00 N/A N/A
ENST00000561066 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.950±0.00
ENST00000561075 N/A N/A N/A N/A N/A N/A N/A N/A 0.220±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000504 CIL_000504_0002 CGP 15:51056598-51338610
CIL_0007YR CIL_0007YR_0001 VISTA 15:51100773-51703779
CIL_000507 CIL_000507_0002 CGP 15:51208057-51408013

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005506 IEA iron ion binding
GO:0005783 IDA endoplasmic reticulum
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006694 TAS steroid biosynthetic process
GO:0006703 TAS estrogen biosynthetic process
GO:0006805 TAS xenobiotic metabolic process
GO:0008202 TAS steroid metabolic process
GO:0008209 IEA androgen metabolic process
GO:0009055 TAS electron carrier activity
GO:0016020 TAS membrane
GO:0016125 TAS sterol metabolic process
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016712 TAS oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
GO:0019825 TAS oxygen binding
GO:0020037 IEA:IDA heme binding
GO:0044281 TAS small molecule metabolic process
GO:0055114 IEA oxidation-reduction process
GO:0060736 IEA prostate gland growth
GO:0070330 IDA aromatase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009852 cyp19a1b cytochrome P450, family 19, subfamily A, polypeptide 1b protein_coding Danio_rerio
ENSDARG00000041348 cyp19a1a cytochrome P450, family 19, subfamily A, polypeptide 1a protein_coding Danio_rerio
ENSMUSG00000032274 Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 protein_coding Mus_musculus

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