C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: kinase suppressor of ras 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000141068 KSR1 9606 + 17:27456714-27626438 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000268763 KSR1-201 27472010-27623392 protein_coding
  ENST00000398982 KSR1-011 27582921-27622144 protein_coding
  ENST00000398985 KSR1-003 27560317-27579878 retained_intron
  ENST00000398988 KSR1-001 27472010-27626438 protein_coding
  ENST00000509603 KSR1-202 27472010-27617742 protein_coding
  ENST00000577823 KSR1-015 27583009-27592614 nonsense_mediated_decay
  ENST00000578981 KSR1-019 27621035-27623822 protein_coding
  ENST00000579309 KSR1-006 27456730-27483855 processed_transcript
  ENST00000579399 KSR1-009 27577456-27585960 retained_intron
  ENST00000579961 KSR1-002 27592558-27604728 processed_transcript
  ENST00000580163 KSR1-005 27456714-27582674 protein_coding
  ENST00000580430 KSR1-017 27610128-27623455 protein_coding
  ENST00000580822 KSR1-014 27587112-27590855 processed_transcript
  ENST00000581975 KSR1-010 27585848-27604728 processed_transcript
  ENST00000582311 KSR1-008 27472013-27582935 processed_transcript
  ENST00000582410 KSR1-012 27609843-27623694 protein_coding
  ENST00000583370 KSR1-007 27472005-27583002 protein_coding
  ENST00000583525 KSR1-013 27601290-27605645 retained_intron
  ENST00000583998 KSR1-018 27611309-27617428 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonHeartLungMuscleOvaryPlacentaTestisENST00000398982ENST00000398988ENST00000509603ENST00000581975ENST00000582410
Transcript ID Adrenal Brain Breast Colon Heart Lung Muscle Ovary Placenta Testis
ENST00000398982 N/A 1.411±0.00 N/A N/A N/A N/A 6.076±0.00 N/A 14.116±0.00 24.308±0.00
ENST00000398988 5.790±0.00 N/A 1.155±0.00 0.872±0.00 0.687±0.00 1.187±0.00 N/A 4.475±0.00 N/A N/A
ENST00000509603 N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.253±0.00
ENST00000581975 N/A N/A N/A N/A N/A N/A N/A 7.583±0.00 N/A N/A
ENST00000582410 N/A 1.144±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007SM CIL_0007SM_0001 VISTA 17:27271510-27874835

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA:NAS protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005078 IEA MAP-kinase scaffold activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005783 IEA endoplasmic reticulum
GO:0006468 IEA protein phosphorylation
GO:0007265 NAS Ras protein signal transduction
GO:0016020 IDA membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0031434 IEA mitogen-activated protein kinase kinase binding
GO:0035556 IEA intracellular signal transduction
GO:0043410 IEA positive regulation of MAPK cascade
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000030933 KSR1 (1 of 2) kinase suppressor of ras 1 protein_coding Danio_rerio
ENSDARG00000068714 KSR1 (2 of 2) kinase suppressor of ras 1 protein_coding Danio_rerio
ENSMUSG00000018334 Ksr1 kinase suppressor of ras 1 protein_coding Mus_musculus

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