C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: kinase suppressor of ras 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000018334 Ksr1 10090 - 11:79013440-79146407 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000018478 Ksr1-001 79013440-79146407 protein_coding
  ENSMUST00000108264 Ksr1-004 79026707-79146407 protein_coding
  ENSMUST00000129463 Ksr1-002 79045183-79057627 protein_coding
  ENSMUST00000141409 Ksr1-003 79044920-79059875 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000018478ENSMUST00000108264
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000018478 10.301±0.90 3.773±1.26 5.211±0.52 2.776±0.87 8.389±1.13 5.270±1.05 2.301±0.16 2.378±0.78 0.931±0.97 6.945±1.13 14.585±6.40 3.735±1.26 0.439±0.12
ENSMUST00000108264 N/A 1.521±0.47 N/A N/A 2.627±0.16 5.519±0.00 N/A 0.779±0.00 N/A N/A N/A N/A 0.533±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007SM CIL_0007SM_0002 VISTA 11:78750979-79355443
CIL_0006M1 CIL_0006M1_0002 CGP 11:78962974-79146407
CIL_0001AY CIL_0001AY_0002 CGP 11:79013440-79254671

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0005078 IDA MAP-kinase scaffold activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005783 IEA endoplasmic reticulum
GO:0006468 IEA protein phosphorylation
GO:0016020 IEA membrane
GO:0031434 IEA mitogen-activated protein kinase kinase binding
GO:0035556 IEA intracellular signal transduction
GO:0043410 IDA positive regulation of MAPK cascade
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000030933 KSR1 (1 of 2) kinase suppressor of ras 1 protein_coding Danio_rerio
ENSDARG00000068714 KSR1 (2 of 2) kinase suppressor of ras 1 protein_coding Danio_rerio
ENSG00000141068 KSR1 kinase suppressor of ras 1 protein_coding Homo_sapiens

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