C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: GRB2 associated, regulator of MAPK1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000141441 GAREM 9606 - 18:32124877-32470484 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000269209 GAREM-002 32267500-32470432 protein_coding
  ENST00000399218 GAREM-001 32263522-32470484 protein_coding
  ENST00000578619 GAREM-003 32287876-32331670 processed_transcript
  ENST00000583696 GAREM-004 32124877-32287095 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000269209ENST00000399218
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000269209 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.174±0.00 N/A 0.507±0.00 0.495±0.00 N/A
ENST00000399218 1.306±0.00 0.337±0.00 0.479±0.00 1.464±0.00 1.211±0.59 1.188±0.66 0.976±0.56 0.987±0.00 0.920±0.23 0.685±0.02 0.807±0.56 0.741±0.08 1.006±0.46 1.617±0.57

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003X2 CIL_0003X2_0001 CGP 18:32018372-32131561

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005886 NAS plasma membrane
GO:0007173 IDA epidermal growth factor receptor signaling pathway
GO:0008284 IDA positive regulation of cell proliferation
GO:0051781 IEA positive regulation of cell division
GO:0070064 IDA proline-rich region binding
GO:0070374 IMP positive regulation of ERK1 and ERK2 cascade
GO:0071364 IDA cellular response to epidermal growth factor stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017242 garem GRB2 associated, regulator of MAPK1 protein_coding Danio_rerio
ENSMUSG00000042680 Garem GRB2 associated, regulator of MAPK1 protein_coding Mus_musculus

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