C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: solute carrier family 6 (neurotransmitter transporter), member 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000142319 SLC6A3 9606 - 5:1392790-1445430 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000270349 SLC6A3-001 1392790-1445430 protein_coding
  ENST00000511750 SLC6A3-004 1414741-1416578 retained_intron
  ENST00000512002 SLC6A3-003 1394029-1401307 protein_coding
  ENST00000513308 SLC6A3-002 1416028-1442975 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonHeartKidneyLungOvaryTestisENST00000270349ENST00000512002ENST00000513308
Transcript ID Adrenal Brain Breast Colon Heart Kidney Lung Ovary Testis
ENST00000270349 0.029±0.00 0.014±0.00 N/A 0.080±0.00 N/A 0.044±0.00 0.057±0.00 0.168±0.08 0.115±0.00
ENST00000512002 N/A N/A 0.166±0.00 N/A N/A N/A 0.038±0.00 0.113±0.03 0.168±0.00
ENST00000513308 0.031±0.00 N/A N/A N/A 0.054±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006VY CIL_0006VY_0002 CGP 5:1392790-1523977

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002020 IEA protease binding
GO:0005102 IEA receptor binding
GO:0005328 IEA neurotransmitter:sodium symporter activity
GO:0005329 IDA dopamine transmembrane transporter activity
GO:0005330 IEA dopamine:sodium symporter activity
GO:0005515 IPI protein binding
GO:0005737 TAS cytoplasm
GO:0005886 IDA plasma membrane
GO:0005887 IEA integral component of plasma membrane
GO:0006836 IEA neurotransmitter transport
GO:0007268 TAS synaptic transmission
GO:0007568 IEA aging
GO:0007595 IEA lactation
GO:0007608 IEA sensory perception of smell
GO:0007626 IEA locomotory behavior
GO:0008144 IEA drug binding
GO:0008219 IEA cell death
GO:0008504 IDA monoamine transmembrane transporter activity
GO:0010039 IEA response to iron ion
GO:0014070 IEA response to organic cyclic compound
GO:0015844 IDA monoamine transport
GO:0015872 IDA dopamine transport
GO:0016021 IEA:TAS integral component of membrane
GO:0021984 IEA adenohypophysis development
GO:0030424 IDA axon
GO:0032403 IEA protein complex binding
GO:0035094 IEA response to nicotine
GO:0035240 IEA dopamine binding
GO:0040018 IEA positive regulation of multicellular organism growth
GO:0042053 IEA regulation of dopamine metabolic process
GO:0042136 TAS neurotransmitter biosynthetic process
GO:0042220 IEA response to cocaine
GO:0042416 IEA dopamine biosynthetic process
GO:0042420 IEA dopamine catabolic process
GO:0042493 IEA response to drug
GO:0043005 IEA neuron projection
GO:0043025 IDA neuronal cell body
GO:0045471 IEA response to ethanol
GO:0047485 IEA protein N-terminus binding
GO:0051591 IEA response to cAMP
GO:0055085 TAS transmembrane transport
GO:0060134 IEA prepulse inhibition
GO:0098655 IEA cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004219 SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 protein_coding Danio_rerio
ENSMUSG00000021609 Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 protein_coding Mus_musculus

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