C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: B-cell CLL/lymphoma 10
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000142867 BCL10 9606 - 1:85266248-85277090 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000370580 BCL10-001 85266248-85277090 protein_coding
  ENST00000620248 BCL10-201 85267624-85276456 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000370580ENST00000620248
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000370580 2.713±0.00 2.105±0.00 1.857±0.00 0.898±0.18 1.701±0.85 3.101±0.66 0.773±0.14 2.613±0.75 1.984±0.23 3.265±1.43 1.391±0.00 2.644±0.33 2.606±0.66 2.833±0.02
ENST00000620248 2.876±0.00 2.842±0.00 N/A 1.664±0.42 3.223±0.14 4.255±1.65 0.692±0.22 2.547±1.27 2.484±0.00 3.941±1.67 N/A 3.489±1.25 2.004±1.20 4.965±0.98

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007QR CIL_0007QR_0001 VISTA 1:84924957-85525799

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001772 IEA immunological synapse
GO:0001783 IEA B cell apoptotic process
GO:0001843 ISS neural tube closure
GO:0002020 IPI protease binding
GO:0002224 IC toll-like receptor signaling pathway
GO:0002237 IEP response to molecule of bacterial origin
GO:0002250 TAS adaptive immune response
GO:0002906 IDA negative regulation of mature B cell apoptotic process
GO:0003713 IDA transcription coactivator activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005764 IDA lysosome
GO:0005829 IDA cytosol
GO:0005881 IDA cytoplasmic microtubule
GO:0005886 TAS plasma membrane
GO:0006968 IEA cellular defense response
GO:0008022 IPI protein C-terminus binding
GO:0008134 IPI transcription factor binding
GO:0008219 IDA cell death
GO:0009620 IEA response to fungus
GO:0016064 IEA immunoglobulin mediated immune response
GO:0019209 IDA kinase activator activity
GO:0019899 IPI enzyme binding
GO:0019900 IPI kinase binding
GO:0019901 IDA protein kinase binding
GO:0031398 IDA positive regulation of protein ubiquitination
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032094 IDA response to food
GO:0032449 NAS CBM complex
GO:0032765 NAS positive regulation of mast cell cytokine production
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0042101 IDA T cell receptor complex
GO:0042109 NAS lymphotoxin A biosynthetic process
GO:0042226 NAS interleukin-6 biosynthetic process
GO:0042327 IDA positive regulation of phosphorylation
GO:0042981 IEA regulation of apoptotic process
GO:0043123 IEP positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043130 IDA ubiquitin binding
GO:0043234 IDA protein complex
GO:0043280 IEA positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043422 IPI protein kinase B binding
GO:0043621 IPI protein self-association
GO:0045087 IEP innate immune response
GO:0045121 IEA membrane raft
GO:0045416 IMP positive regulation of interleukin-8 biosynthetic process
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0046696 IDA lipopolysaccharide receptor complex
GO:0048471 IDA perinuclear region of cytoplasm
GO:0050852 IDA T cell receptor signaling pathway
GO:0050856 IEA regulation of T cell receptor signaling pathway
GO:0050870 IEA positive regulation of T cell activation
GO:0051059 IDA NF-kappaB binding
GO:0051092 IDA positive regulation of NF-kappaB transcription factor activity
GO:0051259 IPI protein oligomerization
GO:0051260 ISS protein homooligomerization
GO:0070231 IEA T cell apoptotic process
GO:0071260 IEP cellular response to mechanical stimulus
GO:2001238 IDA positive regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077130 bcl10 B-cell CLL/lymphoma 10 protein_coding Danio_rerio
ENSMUSG00000028191 Bcl10 B cell leukemia/lymphoma 10 protein_coding Mus_musculus

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