C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: B cell leukemia/lymphoma 10
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028191 Bcl10 10090 + 3:145924378-145934283 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000029842 Bcl10-201 145924378-145934283 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000029842
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000029842 8.495±0.54 2.472±1.42 12.371±0.78 3.812±0.96 6.901±1.30 11.355±2.30 5.473±0.49 7.560±0.94 5.482±2.29 6.962±0.77 5.030±0.34 4.415±1.74 10.917±2.89 2.645±0.77

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007QR CIL_0007QR_0002 VISTA 3:145664099-146264929

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001772 IDA immunological synapse
GO:0001783 IDA B cell apoptotic process
GO:0001843 IMP neural tube closure
GO:0002020 IEA protease binding
GO:0002237 ISS response to molecule of bacterial origin
GO:0002906 ISS negative regulation of mature B cell apoptotic process
GO:0003713 ISS transcription coactivator activity
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0005764 ISS lysosome
GO:0005829 ISS cytosol
GO:0005881 ISS cytoplasmic microtubule
GO:0006919 ISA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006968 IMP cellular defense response
GO:0007249 ISO I-kappaB kinase/NF-kappaB signaling
GO:0008022 ISS protein C-terminus binding
GO:0008134 ISS transcription factor binding
GO:0008219 ISS cell death
GO:0008656 ISA cysteine-type endopeptidase activator activity involved in apoptotic process
GO:0009620 IMP response to fungus
GO:0016064 IMP immunoglobulin mediated immune response
GO:0019209 ISS kinase activator activity
GO:0019899 IEA enzyme binding
GO:0019900 ISS kinase binding
GO:0019901 ISS protein kinase binding
GO:0031398 ISS positive regulation of protein ubiquitination
GO:0031625 ISS ubiquitin protein ligase binding
GO:0032094 ISS response to food
GO:0032449 IBA CBM complex
GO:0042101 ISS T cell receptor complex
GO:0042327 ISS positive regulation of phosphorylation
GO:0042803 ISA protein homodimerization activity
GO:0043065 ISA positive regulation of apoptotic process
GO:0043123 ISS positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043130 ISS ubiquitin binding
GO:0043234 ISS protein complex
GO:0043280 IDA positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043422 ISS protein kinase B binding
GO:0043621 ISS protein self-association
GO:0045087 ISS innate immune response
GO:0045121 IDA membrane raft
GO:0045416 ISS positive regulation of interleukin-8 biosynthetic process
GO:0045576 NAS mast cell activation
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0046696 ISS lipopolysaccharide receptor complex
GO:0046982 ISA protein heterodimerization activity
GO:0048471 ISS perinuclear region of cytoplasm
GO:0050852 ISS T cell receptor signaling pathway
GO:0050856 IMP regulation of T cell receptor signaling pathway
GO:0050870 IMP positive regulation of T cell activation
GO:0051059 ISS NF-kappaB binding
GO:0051092 ISS positive regulation of NF-kappaB transcription factor activity
GO:0051259 ISS protein oligomerization
GO:0051260 IMP protein homooligomerization
GO:0070231 IDA T cell apoptotic process
GO:0071260 IEA cellular response to mechanical stimulus
GO:1900119 ISO positive regulation of execution phase of apoptosis
GO:2001238 ISS positive regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077130 bcl10 B-cell CLL/lymphoma 10 protein_coding Danio_rerio
ENSG00000142867 BCL10 B-cell CLL/lymphoma 10 protein_coding Homo_sapiens

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