C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ATPase, Na+/K+ transporting, beta 1 polypeptide
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000143153 ATP1B1 9606 + 1:169105697-169132722 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000367815 ATP1B1-001 169106323-169132019 protein_coding
  ENST00000367816 ATP1B1-002 169105697-169132722 protein_coding
  ENST00000494797 ATP1B1-003 169107907-169127399 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartLiverLungMuscleOvaryPlacentaTestisENST00000367815ENST00000367816ENST00000494797
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Liver Lung Muscle Ovary Placenta Testis
ENST00000367815 1.572±0.00 N/A N/A N/A N/A N/A 61.090±0.00 N/A 17.525±0.00 131.132±0.00 38.788±25.12 8.012±3.09 26.405±0.00
ENST00000367816 2.401±0.00 4.292±0.00 163.569±0.00 44.903±0.00 30.854±0.00 46.749±0.00 31.249±11.35 3.476±0.00 N/A 89.174±0.00 57.716±26.99 7.894±2.76 20.806±0.00
ENST00000494797 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 96.064±0.00 14.064±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000281 CIL_000281_0002 CGP 1:168695459-169132722
CIL_000282 CIL_000282_0002 CGP 1:169105697-169367967

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 IEA response to hypoxia
GO:0001671 IDA ATPase activator activity
GO:0005391 IDA sodium:potassium-exchanging ATPase activity
GO:0005515 IPI protein binding
GO:0005886 IDA plasma membrane
GO:0005890 IDA:IEA sodium:potassium-exchanging ATPase complex
GO:0005901 IEA caveola
GO:0006813 IEA potassium ion transport
GO:0006814 IEA sodium ion transport
GO:0006874 ISS cellular calcium ion homeostasis
GO:0006883 IDA cellular sodium ion homeostasis
GO:0007155 IEA cell adhesion
GO:0007596 TAS blood coagulation
GO:0010107 IDA potassium ion import
GO:0010468 ISS regulation of gene expression
GO:0010882 ISS regulation of cardiac muscle contraction by calcium ion signaling
GO:0014704 ISS intercalated disc
GO:0016323 IEA basolateral plasma membrane
GO:0016324 IEA apical plasma membrane
GO:0023026 IDA MHC class II protein complex binding
GO:0030001 IEA metal ion transport
GO:0030007 IDA cellular potassium ion homeostasis
GO:0031982 IDA vesicle
GO:0032781 IDA positive regulation of ATPase activity
GO:0034220 TAS ion transmembrane transport
GO:0035725 IEA sodium ion transmembrane transport
GO:0036376 IDA sodium ion export from cell
GO:0042383 ISS sarcolemma
GO:0044861 TAS protein transport into plasma membrane raft
GO:0050821 ISS protein stabilization
GO:0050900 TAS leukocyte migration
GO:0051117 IPI ATPase binding
GO:0055085 TAS transmembrane transport
GO:0055119 ISS relaxation of cardiac muscle
GO:0060048 ISS cardiac muscle contraction
GO:0070062 IDA extracellular vesicular exosome
GO:0072659 IDA protein localization to plasma membrane
GO:0086009 IDA membrane repolarization
GO:0086013 IC membrane repolarization during cardiac muscle cell action potential
GO:0086064 TAS cell communication by electrical coupling involved in cardiac conduction
GO:1901018 IDA positive regulation of potassium ion transmembrane transporter activity
GO:1903169 IEA regulation of calcium ion transmembrane transport
GO:1903278 IDA positive regulation of sodium ion export from cell
GO:1903281 ISS positive regulation of calcium:sodium antiporter activity
GO:1903288 IDA positive regulation of potassium ion import
GO:1903291 IDA positive regulation of ATP catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013144 atp1b1a ATPase, Na+/K+ transporting, beta 1a polypeptide protein_coding Danio_rerio
ENSDARG00000076833 atp1b1b ATPase, Na+/K+ transporting, beta 1b polypeptide protein_coding Danio_rerio
ENSMUSG00000026576 Atp1b1 ATPase, Na+/K+ transporting, beta 1 polypeptide protein_coding Mus_musculus

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