C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protoporphyrinogen oxidase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000143224 PPOX 9606 + 1:161166410-161178013 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000352210 PPOX-001 161166410-161171218 protein_coding
  ENST00000367999 PPOX-002 161166415-161171216 protein_coding
  ENST00000460611 PPOX-015 161168395-161169985 processed_transcript
  ENST00000462866 PPOX-016 161166840-161171218 processed_transcript
  ENST00000462977 PPOX-014 161168260-161169840 processed_transcript
  ENST00000466452 PPOX-017 161170261-161171181 processed_transcript
  ENST00000468968 PPOX-007 161166482-161168127 retained_intron
  ENST00000470607 PPOX-009 161166439-161169720 processed_transcript
  ENST00000479246 PPOX-005 161166439-161168545 retained_intron
  ENST00000490768 PPOX-006 161166678-161168406 processed_transcript
  ENST00000494216 PPOX-013 161168095-161169706 processed_transcript
  ENST00000495483 PPOX-003 161166480-161178013 processed_transcript
  ENST00000497522 PPOX-008 161166430-161177041 processed_transcript
  ENST00000535223 PPOX-012 161166498-161177092 protein_coding
  ENST00000537523 PPOX-018 161168523-161171218 protein_coding
  ENST00000537829 PPOX-020 161169685-161171218 protein_coding
  ENST00000539753 PPOX-010 161166452-161170949 nonsense_mediated_decay
  ENST00000541818 PPOX-019 161169284-161171181 retained_intron
  ENST00000544598 PPOX-011 161166470-161171220 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastLiverLungPlacentaTestisENST00000352210ENST00000367999ENST00000462866ENST00000462977ENST00000544598
Transcript ID Brain Breast Liver Lung Placenta Testis
ENST00000352210 2.464±0.00 N/A 0.907±0.00 N/A N/A N/A
ENST00000367999 1.698±0.00 4.246±0.00 N/A 0.841±0.00 8.456±0.00 4.618±0.00
ENST00000462866 5.411±0.00 N/A N/A N/A N/A N/A
ENST00000462977 N/A N/A N/A 1.262±0.00 N/A N/A
ENST00000544598 4.411±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004729 IDA:IEA oxygen-dependent protoporphyrinogen oxidase activity
GO:0005739 IEA mitochondrion
GO:0005758 TAS mitochondrial intermembrane space
GO:0006778 TAS porphyrin-containing compound metabolic process
GO:0006779 IDA:IEA porphyrin-containing compound biosynthetic process
GO:0006782 IEA protoporphyrinogen IX biosynthetic process
GO:0006783 IDA heme biosynthetic process
GO:0016491 IEA oxidoreductase activity
GO:0031304 ISS intrinsic component of mitochondrial inner membrane
GO:0031305 IEA integral component of mitochondrial inner membrane
GO:0031966 IMP mitochondrial membrane
GO:0042493 IEA response to drug
GO:0044281 TAS small molecule metabolic process
GO:0046501 IEA protoporphyrinogen IX metabolic process
GO:0050660 TAS flavin adenine dinucleotide binding
GO:0055114 IDA:IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000025200 ppox protoporphyrinogen oxidase protein_coding Danio_rerio
ENSMUSG00000062729 Ppox protoporphyrinogen oxidase protein_coding Mus_musculus

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