C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protoporphyrinogen oxidase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000062729 Ppox 10090 - 1:171275990-171281186 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000073120 Ppox-001 171276992-171281186 protein_coding
  ENSMUST00000126765 Ppox-007 171278135-171279827 processed_transcript
  ENSMUST00000133050 Ppox-004 171280365-171281119 retained_intron
  ENSMUST00000145019 Ppox-006 171279862-171280522 processed_transcript
  ENSMUST00000151442 Ppox-005 171280109-171281186 retained_intron
  ENSMUST00000152689 Ppox-003 171276992-171281186 retained_intron
  ENSMUST00000155083 Ppox-002 171275990-171281186 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000073120ENSMUST00000151442ENSMUST00000152689ENSMUST00000155083
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000073120 14.820±2.57 16.023±1.95 19.131±0.57 16.240±6.24 15.662±1.34 12.554±0.50 6.977±1.31 15.214±2.46 35.830±32.24 13.953±0.25 4.531±1.23 21.114±2.06 10.744±0.05 N/A
ENSMUST00000151442 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 28.385±0.00 N/A N/A
ENSMUST00000152689 4.908±0.24 N/A 8.021±0.74 N/A 6.883±0.00 N/A N/A N/A 49.475±18.53 N/A 1.222±0.00 11.946±1.09 N/A N/A
ENSMUST00000155083 9.492±3.84 17.644±1.40 10.752±3.46 15.977±2.46 13.683±4.32 12.618±4.03 4.987±1.11 8.935±2.36 13.539±9.64 12.024±5.27 2.314±0.56 14.472±6.40 8.073±0.08 4.210±0.39

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004729 IDA oxygen-dependent protoporphyrinogen oxidase activity
GO:0005739 IDA mitochondrion
GO:0006779 ISS porphyrin-containing compound biosynthetic process
GO:0006782 IEA protoporphyrinogen IX biosynthetic process
GO:0006783 ISS heme biosynthetic process
GO:0031304 IDA intrinsic component of mitochondrial inner membrane
GO:0031305 IEA integral component of mitochondrial inner membrane
GO:0031966 ISS mitochondrial membrane
GO:0042493 IEA response to drug
GO:0046501 IEA protoporphyrinogen IX metabolic process
GO:0055114 ISS oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000025200 ppox protoporphyrinogen oxidase protein_coding Danio_rerio
ENSG00000143224 PPOX protoporphyrinogen oxidase protein_coding Homo_sapiens

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