C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: integrator complex subunit 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000143624 INTS3 9606 + 1:153728067-153774808 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000318967 INTS3-001 153728067-153774808 protein_coding
  ENST00000368669 INTS3-006 153766831-153774079 retained_intron
  ENST00000368670 INTS3-005 153766475-153774079 retained_intron
  ENST00000435409 INTS3-008 153728091-153773535 protein_coding
  ENST00000476843 INTS3-003 153751135-153774079 nonsense_mediated_decay
  ENST00000480659 INTS3-007 153752077-153760902 retained_intron
  ENST00000481797 INTS3-002 153728483-153774079 retained_intron
  ENST00000491790 INTS3-004 153759674-153762840 retained_intron
  ENST00000503133 INTS3-010 153757637-153773319 nonsense_mediated_decay
  ENST00000512605 INTS3-009 153750854-153773728 protein_coding
  ENST00000624515 INTS3-011 153773034-153774808 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000318967ENST00000435409ENST00000481797ENST00000503133
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000318967 N/A N/A N/A N/A N/A 1.223±0.00 6.498±0.00 1.667±0.00 N/A 1.095±0.79 2.114±0.00 2.285±0.09 N/A
ENST00000435409 6.747±0.00 2.604±0.00 4.625±1.10 6.294±0.00 3.544±1.71 2.739±1.40 9.105±7.29 2.966±0.00 4.367±0.00 3.014±1.72 11.561±6.25 7.653±3.05 11.235±1.54
ENST00000481797 N/A N/A 1.983±0.07 1.750±0.65 1.514±0.00 0.869±0.17 1.869±0.00 N/A N/A 0.480±0.00 4.705±1.62 N/A 9.784±0.00
ENST00000503133 N/A N/A N/A N/A 5.603±0.00 N/A N/A N/A 7.661±0.00 N/A 13.673±0.00 9.574±0.00 13.560±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000LZ CIL_0000LZ_0002 CGP 1:153678637-153774808

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006281 IMP DNA repair
GO:0006974 IMP cellular response to DNA damage stimulus
GO:0007093 IMP mitotic cell cycle checkpoint
GO:0010212 IMP response to ionizing radiation
GO:0016180 IDA snRNA processing
GO:0032039 IDA integrator complex
GO:0070876 IDA SOSS complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016811 ints3 integrator complex subunit 3 protein_coding Danio_rerio
ENSMUSG00000027933 Ints3 integrator complex subunit 3 protein_coding Mus_musculus

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