C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: pyruvate kinase, liver and RBC
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000143627 PKLR 9606 - 1:155289839-155301434 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000342741 PKLR-001 155290253-155301434 protein_coding
  ENST00000392414 PKLR-002 155289839-155301001 protein_coding
  ENST00000434082 PKLR-004 155295135-155300956 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainColonKidneyLiverPlacentaTestisENST00000342741ENST00000392414
Transcript ID Bladder Brain Colon Kidney Liver Placenta Testis
ENST00000342741 2.322±0.00 0.309±0.00 0.237±0.00 N/A 0.040±0.00 0.108±0.02 0.815±0.24
ENST00000392414 1.269±0.00 N/A N/A 1.820±0.00 3.662±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 IEA magnesium ion binding
GO:0001666 IEA response to hypoxia
GO:0003824 IEA catalytic activity
GO:0004743 NAS:IEA pyruvate kinase activity
GO:0005524 IEA ATP binding
GO:0005575 ND cellular_component
GO:0005829 TAS cytosol
GO:0005975 TAS carbohydrate metabolic process
GO:0006006 TAS glucose metabolic process
GO:0006096 IEA glycolytic process
GO:0006112 TAS energy reserve metabolic process
GO:0006754 IEA ATP biosynthetic process
GO:0007584 IEA response to nutrient
GO:0009408 IEA response to heat
GO:0009749 IEA response to glucose
GO:0010038 IEA response to metal ion
GO:0010226 IEA response to lithium ion
GO:0014070 IEA response to organic cyclic compound
GO:0016310 IEA phosphorylation
GO:0030955 IEA potassium ion binding
GO:0031018 TAS endocrine pancreas development
GO:0031325 TAS positive regulation of cellular metabolic process
GO:0032869 IEA cellular response to insulin stimulus
GO:0033198 IEA response to ATP
GO:0042866 IEA pyruvate biosynthetic process
GO:0044281 TAS small molecule metabolic process
GO:0051591 IEA response to cAMP
GO:0051707 IEA response to other organism
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042010 CABZ01066502.1 Pyruvate kinase protein_coding Danio_rerio
ENSMUSG00000041237 Pklr pyruvate kinase liver and red blood cell protein_coding Mus_musculus

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