C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: pyruvate kinase liver and red blood cell
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000041237 Pklr 10090 + 3:89136142-89146784 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000047111 Pklr-001 89136142-89146594 protein_coding
  ENSMUST00000107482 Pklr-002 89136572-89146784 protein_coding
  ENSMUST00000127058 Pklr-003 89136579-89141539 protein_coding
  ENSMUST00000148097 Pklr-004 89136623-89140912 processed_transcript
  ENSMUST00000151591 Pklr-005 89136174-89137459 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeColonHeartKidneyLiverLungOvaryPlacentaENSMUST00000047111ENSMUST00000107482ENSMUST00000127058
Transcript ID Adipose Colon Heart Kidney Liver Lung Ovary Placenta
ENSMUST00000047111 N/A 11.103±3.09 0.022±0.01 5.650±0.73 64.451±35.36 0.168±0.03 1.289±0.36 4.644±5.48
ENSMUST00000107482 N/A 7.501±2.47 N/A 3.106±0.50 N/A N/A N/A N/A
ENSMUST00000127058 0.169±0.00 100.946±9.97 N/A 43.261±0.00 263.725±60.39 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 IEA magnesium ion binding
GO:0001666 IEA response to hypoxia
GO:0004743 IDA pyruvate kinase activity
GO:0005829 IEA cytosol
GO:0005975 IEA carbohydrate metabolic process
GO:0006096 IEA glycolytic process
GO:0006754 IEA ATP biosynthetic process
GO:0007584 IEA response to nutrient
GO:0009408 IEA response to heat
GO:0009749 IEA response to glucose
GO:0010038 IEA response to metal ion
GO:0010226 IEA response to lithium ion
GO:0014070 IEA response to organic cyclic compound
GO:0016310 IEA phosphorylation
GO:0030955 IEA potassium ion binding
GO:0032869 IEA cellular response to insulin stimulus
GO:0033198 IEA response to ATP
GO:0042866 IEA pyruvate biosynthetic process
GO:0051591 IEA response to cAMP
GO:0051707 IMP response to other organism
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042010 CABZ01066502.1 Pyruvate kinase protein_coding Danio_rerio
ENSG00000143627 PKLR pyruvate kinase, liver and RBC protein_coding Homo_sapiens

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