C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: renin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000143839 REN 9606 - 1:204154819-204166322 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000272190 REN-001 204154819-204166322 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverLungOvaryPlacentaTestisENST00000272190
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Lung Ovary Placenta Testis
ENST00000272190 0.083±0.00 0.074±0.00 6.943±0.00 0.080±0.05 0.161±0.00 1.470±0.00 14.580±0.00 0.120±0.00 0.099±0.01 3.981±3.24 4.939±1.02 1.366±0.89

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008W2 CIL_0008W2_0001 VISTA 1:203635137-204239984

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001822 IMP kidney development
GO:0001823 IEA mesonephros development
GO:0002003 IDA angiotensin maturation
GO:0002016 IEA regulation of blood volume by renin-angiotensin
GO:0002018 IEA renin-angiotensin regulation of aldosterone production
GO:0004175 IEA endopeptidase activity
GO:0004190 IDA:IEA aspartic-type endopeptidase activity
GO:0005102 IPI receptor binding
GO:0005159 IEA insulin-like growth factor receptor binding
GO:0005576 TAS extracellular region
GO:0005615 IDA extracellular space
GO:0005622 IEA intracellular
GO:0005737 IEA cytoplasm
GO:0005886 TAS plasma membrane
GO:0006508 IDA:IEA proteolysis
GO:0008217 TAS regulation of blood pressure
GO:0008233 IDA peptidase activity
GO:0008584 IEA male gonad development
GO:0009755 IEA hormone-mediated signaling pathway
GO:0010033 IEA response to organic substance
GO:0032496 IEA response to lipopolysaccharide
GO:0035690 IEA cellular response to drug
GO:0035902 IEA response to immobilization stress
GO:0042493 IEA response to drug
GO:0042756 IEA drinking behavior
GO:0043408 IDA regulation of MAPK cascade
GO:0044267 TAS cellular protein metabolic process
GO:0048469 IEA cell maturation
GO:0050435 IEA beta-amyloid metabolic process
GO:0051591 IEA response to cAMP
GO:0070305 IEA response to cGMP

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041858 ren renin protein_coding Danio_rerio
ENSMUSG00000070645 Ren1 renin 1 structural protein_coding Mus_musculus

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